Gene name: CIR1

Uniprot entry:

Q86X95

Protein names:

Corepressor interacting with RBPJ 1 (CBF1-interacting corepressor) (Recepin)

Protein sequence:

1_MGKSF 6_ ANFMC 11_ KKDFH 16_ PASKS 21_ NIKKV 26_ WMAEQ 31_ KISYD 36_ KKKQE 41_ ELMQQ 46_ YLKEQ 51_ ESYDN 56_ RLLMG 61_ DERVK 66_ NGLNF 71_ MYEAP 76_ PGAKK 81_ ENKEK 86_ EETEG 91_ ETEYK 96_ FEWQK 101_ GAPRE 106_ KYAKD 111_ DMNIR 116_ DQPFG 121_ IQVRN 126_ VRCIK 131_ CHKWG 136_ HVNTD 141_ RECPL 146_ FGLSG 151_ INASS 156_ VPTDG 161_ SGPSM 166_ HPSEL 171_ IAEMR 176_ NSGFA 181_ LKRNV 186_ LGRNL 191_ TANDP 196_ SQEYV 201_ ASEGE 206_ EDPEV 211_ EFLKS 216_ LTTKQ 221_ KQKLL 226_ RKLDR 231_ LEKKK 236_ KKKDR 241_ KKKKF 246_ QKSRS 251_ KHKKH 256_ KSSSS 261_ SSSSS 266_ SSSSS 271_ TETSE 276_ SSSES 281_ ESNNK 286_ EKKIQ 291_ RKKRK 296_ KNKCS 301_ GHNNS 306_ DSEEK 311_ DKSKK 316_ RKLHE 321_ ELSSS 326_ HHNRE 331_ KAKEK 336_ PRFLK 341_ HESSR 346_ EDSKW 351_ SHSDS 356_ DKKSR 361_ THKHS 366_ PEKRG 371_ SERKE 376_ GSSRS 381_ HGREE 386_ RSRRS 391_ RSRSP 396_ GSYKQ 401_ RETRK 406_ RAQRN 411_ PGEEQ 416_ SRRND 421_ SRSHG 426_ TDLYR 431_ GEKMY 436_ REHPG 441_GTHTK

Protein annotations

Protein functions:

1: May modulate splice site selection during alternative splicing of pre-mRNAs (By similarity). Regulates transcription and acts as corepressor for RBPJ. Recruits RBPJ to the Sin3-histone deacetylase complex (HDAC). Required for RBPJ-mediated repression of transcription