All trans-polyprenyl-diphosphate synthase PDSS2 (All-trans-decaprenyl-diphosphate synthase subunit 2) (EC 2.5.1.91) (Candidate tumor suppressor protein) (Decaprenyl pyrophosphate synthase subunit 2) (Decaprenyl-diphosphate synthase subunit 2) (Solanesyl-diphosphate synthase subunit 2)
1_MNFRQ 6_ LLLHL 11_ PRYLG 16_ ASGSP 21_ RRLWW 26_ SPSLD 31_ TISSV 36_ GSWRG 41_ RSSKS 46_ PAHWN 51_ QVVSE 56_ AEKIV 61_ GYPTS 66_ FMSLR 71_ CLLSD 76_ ELSNI 81_ AMQVR 86_ KLVGT 91_ QHPLL 96_ TTARG 101_ LVHDS 106_ WNSLQ 111_ LRGLV 116_ VLLIS 121_ KAAGP 126_ SSVNT 131_ SCQNY 136_ DMVSG 141_ IYSCQ 146_ RSLAE 151_ ITELI 156_ HIALL 161_ VHRGI 166_ VNLNE 171_ LQSSD 176_ GPLKD 181_ MQFGN 186_ KIAIL 191_ SGDFL 196_ LANAC 201_ NGLAL 206_ LQNTK 211_ VVELL 216_ ASALM 221_ DLVQG 226_ VYHEN 231_ STSKE 236_ SYITD 241_ DIGIS 246_ TWKEQ 251_ TFLSH 256_ GALLA 261_ KSCQA 266_ AMELA 271_ KHDAE 276_ VQNMA 281_ FQYGK 286_ HMAMS 291_ HKINS 296_ DVQPF 301_ IKEKT 306_ SDSMT 311_ FNLNS 316_ APVVL 321_ HQEFL 326_ GRDLW 331_ IKQIG 336_ EAQEK 341_ GRLDY 346_ AKLRE 351_ RIKAG 356_ KGVTS 361_ AIDLC 366_ RYHGN 371_ KALEA 376_ LESFP 381_ PSEAR 386_ SALEN 391_IVFAV
1: Heterotetrameric enzyme that catalyzes the condensation of farnesyl diphosphate (FPP), which acts as a primer, and isopentenyl diphosphate (IPP) to produce prenyl diphosphates of varying chain lengths and participates in the determination of the side chain of ubiquinone (PubMed:16262699). Supplies nona and decaprenyl diphosphate, the precursors for the side chain of the isoprenoid quinones ubiquinone-9 (Q9) and ubiquinone-10 (Q10) respectively (PubMed:16262699). The enzyme adds isopentenyl diphosphate molecules sequentially to farnesyl diphosphate with trans stereochemistry (PubMed:16262699). May play a role during cerebellar development (By similarity). May regulate mitochondrial respiratory chain function (By similarity)