Transcriptional repressor p66-alpha (Hp66alpha) (GATA zinc finger domain-containing protein 2A)
1_MTEEA 6_ CRTRS 11_ QKRAL 16_ ERDPT 21_ EDDVE 26_ SKKIK 31_ MERGL 36_ LASDL 41_ NTDGD 46_ MRVTP 51_ EPGAG 56_ PTQGL 61_ LRATE 66_ ATAMA 71_ MGRGE 76_ GLVGD 81_ GPVDM 86_ RTSHS 91_ DMKSE 96_ RRPPS 101_ PDVIV 106_ LSDNE 111_ QPSSP 116_ RVNGL 121_ TTVAL 126_ KETST 131_ EALMK 136_ SSPEE 141_ RERMI 146_ KQLKE 151_ ELRLE 156_ EAKLV 161_ LLKKL 166_ RQSQI 171_ QKEAT 176_ AQKPT 181_ GSVGS 186_ TVTTP 191_ PPLVR 196_ GTQNI 201_ PAGKP 206_ SLQTS 211_ SARMP 216_ GSVIP 221_ PPLVR 226_ GGQQA 231_ SSKLG 236_ PQASS 241_ QVVMP 246_ PLVRG 251_ AQQIH 256_ SIRQH 261_ SSTGP 266_ PPLLL 271_ APRAS 276_ VPSVQ 281_ IQGQR 286_ IIQQG 291_ LIRVA 296_ NVPNT 301_ SLLVN 306_ IPQPT 311_ PASLK 316_ GTTAT 321_ SAQAN 326_ STPTS 331_ VASVV 336_ TSAES 341_ PASRQ 346_ AAAKL 351_ ALRKQ 356_ LEKTL 361_ LEIPP 366_ PKPPA 371_ PEMNF 376_ LPSAA 381_ NNEFI 386_ YLVGL 391_ EEVVQ 396_ NLLET 401_ QGRMS 406_ AATVL 411_ SREPY 416_ MCAQC 421_ KTDFT 426_ CRWRE 431_ EKSGA 436_ IMCEN 441_ CMTTN 446_ QKKAL 451_ KVEHT 456_ SRLKA 461_ AFVKA 466_ LQQEQ 471_ EIEQR 476_ LLQQG 481_ TAPAQ 486_ AKAEP 491_ TAAPH 496_ PVLKQ 501_ VIKPR 506_ RKLAF 511_ RSGEA 516_ RDWSN 521_ GAVLQ 526_ ASSQL 531_ SRGSA 536_ TTPRG 541_ VLHTF 546_ SPSPK 551_ LQNSA 556_ SATAL 561_ VSRTG 566_ RHSER 571_ TVSAG 576_ KGSAT 581_ SNWKK 586_ TPLST 591_ GGTLA 596_ FVSPS 601_ LAVHK 606_ SSSAV 611_ DRQRE 616_ YLLDM 621_ IPPRS 626_IPQSA
1: Transcriptional repressor (PubMed:12183469, PubMed:16415179). Acts as a component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin (PubMed:16428440, PubMed:28977666). Enhances MBD2-mediated repression (PubMed:12183469, PubMed:16415179). Efficient repression requires the presence of GATAD2B (PubMed:16415179)