Formin-like protein 3 (Formin homology 2 domain-containing protein 3) (WW domain-binding protein 3) (WBP-3)
1_MGNLE 6_ SAEGV 11_ PGEPP 16_ SVPLL 21_ LPPGK 26_ MPMPE 31_ PCELE 36_ ERFAL 41_ VLSSM 46_ NLPPD 51_ KARLL 56_ RQYDN 61_ EKKWD 66_ LICDQ 71_ ERFQV 76_ KNPPH 81_ TYIQK 86_ LQSFL 91_ DPSVT 96_ RKKFR 101_ RRVQE 106_ STKVL 111_ RELEI 116_ SLRTN 121_ HIGWV 126_ REFLN 131_ DENKG 136_ LDVLV 141_ DYLSF 146_ AQCSV 151_ MFDFE 156_ GLESG 161_ DDGAF 166_ DKLRS 171_ WSRSI 176_ EDLQP 181_ PSALS 186_ APFTN 191_ SLARS 196_ ARQSV 201_ LRYST 206_ LPGRR 211_ ALKNS 216_ RLVSQ 221_ KDDVH 226_ VCILC 231_ LRAIM 236_ NYQYG 241_ FNLVM 246_ SHPHA 251_ VNEIA 256_ LSLNN 261_ KNPRT 266_ KALVL 271_ ELLAA 276_ VCLVR 281_ GGHEI 286_ ILAAF 291_ DNFKE 296_ VCKEL 301_ HRFEK 306_ LMEYF 311_ RNEDS 316_ NIDFM 321_ VACMQ 326_ FINIV 331_ VHSVE 336_ DMNFR 341_ VHLQY 346_ EFTKL 351_ GLEEF 356_ LQKSR 361_ HTESE 366_ KLQVQ 371_ IQAYL 376_ DNVFD 381_ VGGLL 386_ EDAET 391_ KNVAL 396_ EKVEE 401_ LEEHV 406_ SHLTE 411_ KLLDL 416_ ENENM 421_ MRVAE 426_ LEKQL 431_ LQREK 436_ ELESI 441_ KETYE 446_ NTSHQ 451_ VHTLR 456_ RLIKE 461_ KEEAF 466_ QRRCH 471_ LEPNV 476_ RGLES 481_ VDSEA 486_ LARVG 491_ PAELS 496_ EGMPP 501_ SDLDL 506_ LAPAP 511_ PPEEV 516_ LPLPP 521_ PPAPP 526_ LPPPP 531_ PPLPD 536_ KCPPA 541_ PPLPG 546_ AAPSV 551_ VLTVG 556_ LSAIR 561_ IKKPI 566_ KTKFR 571_ LPVFN 576_ WTALK 581_ PNQIS 586_ GTVFS 591_ ELDDE 596_ KILED 601_ LDLDK 606_ FEELF 611_ KTKAQ 616_ GPALD 621_ LICSK 626_ NKTAQ 631_ KAASK 636_ VTLLE 641_ ANRAK 646_ NLAIT 651_ LRKAG 656_ RSAEE 661_ ICRAI 666_ HTFDL 671_ QTLPV 676_ DFVEC 681_ LMRFL 686_ PTEAE 691_ VKLLR 696_ QYERE 701_ RQPLE 706_ ELAAE 711_ DRFML 716_ LFSKV 721_ ERLTQ 726_ RMAGM 731_ AFLGN 736_ FQDNL 741_ QMLTP 746_ QLNAI 751_ IAASA 756_ SVKSS 761_ QKLKQ 766_ MLEII 771_ LALGN 776_ YMNSS 781_ KRGAV 786_ YGFKL 791_ QSLDL 796_ LLDTK 801_ STDRK 806_ MTLLH 811_ FIALT 816_ VKEKY 821_ PDLAN 826_ FWHEL 831_ HFVEK 836_ AAAVS 841_ LENVL 846_ LDVKE 851_ LGRGM 856_ ELIRR 861_ ECSIH 866_ DNSVL 871_ RNFLS 876_ TNEGK 881_ LDKLQ 886_ RDAKT 891_ AEEAY 896_ NAVVR 901_ YFGES 906_ PKTTP 911_ PSVFF 916_ PVFVR 921_ FIRSY 926_ KEAEQ 931_ ENEAR 936_ KKQEE 941_ VMREK 946_ QLAQE 951_ AKKLD 956_ AKTPS 961_ QRNKW 966_ QQQEL 971_ IAELR 976_ RRQAK 981_ EHRPV 986_ YEGKD 991_ GTIED 996_ IITVL 1001_ KSVPF 1006_ TARTA 1011_ KRGSR 1016_ FFCDA 1021_AHHDE
1: Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape and migration. Required for developmental angiogenesis (By similarity). In this process, required for microtubule reorganization and for efficient endothelial cell elongation. In quiescent endothelial cells, triggers rearrangement of the actin cytoskeleton, but does not alter microtubule alignement