Solute carrier family 41 member 1
1_MSSKP 6_ EPKDV 11_ HQLNG 16_ TGPSA 21_ SPCSS 26_ DGPGR 31_ EPLAG 36_ TSEFL 41_ GPDGA 46_ GVEVV 51_ IESRA 56_ NAKGV 61_ REEDA 66_ LLENG 71_ SQSNE 76_ SDDVS 81_ TDRGP 86_ APPSP 91_ LKETS 96_ FSIGL 101_ QVLFP 106_ FLLAG 111_ FGTVA 116_ AGMVL 121_ DIVQH 126_ WEVFQ 131_ KVTEV 136_ FILVP 141_ ALLGL 146_ KGNLE 151_ MTLAS 156_ RLSTA 161_ ANIGH 166_ MDTPK 171_ ELWRM 176_ ITGNM 181_ ALIQV 186_ QATVV 191_ GFLAS 196_ IAAVV 201_ FGWIP 206_ DGHFS 211_ IPHAF 216_ LLCAS 221_ SVATA 226_ FIASL 231_ VLGMI 236_ MIGVI 241_ IGSRK 246_ IGINP 251_ DNVAT 256_ PIAAS 261_ LGDLI 266_ TLALL 271_ SGISW 276_ GLYLE 281_ LNHWR 286_ YIYPL 291_ VCAFF 296_ VALLP 301_ VWVVL 306_ ARRSP 311_ ATREV 316_ LYSGW 321_ EPVII 326_ AMAIS 331_ SVGGL 336_ ILDKT 341_ VSDPN 346_ FAGMA 351_ VFTPV 356_ INGVG 361_ GNLVA 366_ VQASR 371_ ISTFL 376_ HMNGM 381_ PGENS 386_ EQAPR 391_ RCPSP 396_ CTTFF 401_ SPDVN 406_ SRSAR 411_ VLFLL 416_ VVPGH 421_ LVFLY 426_ TISCM 431_ QGGHT 436_ TLTLI 441_ FIIFY 446_ MTAAL 451_ LQVLI 456_ LLYIA 461_ DWMVH 466_ WMWGR 471_ GLDPD 476_ NFSIP 481_ YLTAL 486_ GDLLG 491_ TGLLA 496_ LSFHV 501_ LWLIG 506_DRDTD
1: Na(+)/Mg(2+) ion exchanger that acts as a predominant Mg(2+) efflux system at the plasma membrane (PubMed:18367447, PubMed:22031603, PubMed:23661805, PubMed:23976986). Transporter activity is driven by the inwardly directed electrochemical gradient for Na(+) ions, thus directly depends on the extracellular Na(+) ion concentration set by Na(+)/K(+) pump (PubMed:22031603, PubMed:23661805). Generates circadian cellular Mg(2+) fluxes that feed back to regulate clock-controlled gene expression and metabolism and facilitate higher energetic demands during the day (PubMed:27074515). Has a role in regulating the activity of ATP-dependent enzymes, including those operating in Krebs cycle and the electron transport chain (By similarity)