Mitotic interactor and substrate of PLK1 (Mitotic spindle positioning protein)
1_MDRVT 6_ RYPIL 11_ GIPQA 16_ HRGTG 21_ LVLDG 26_ DTSYT 31_ YHLVC 36_ MGPEA 41_ SGWGQ 46_ DEPQT 51_ WPTDH 56_ RAQQG 61_ VQRQG 66_ VSYSV 71_ HAYTG 76_ QPSPR 81_ GLHSE 86_ NREDE 91_ GWQVY 96_ RLGAR 101_ DAHQG 106_ RPTWA 111_ LRPED 116_ GEDKE 121_ MKTYR 126_ LDAGD 131_ ADPRR 136_ LCDLE 141_ RERWA 146_ VIQGQ 151_ AVRKS 156_ STVAT 161_ LQGTP 166_ DHGDP 171_ RTPGP 176_ PRSTP 181_ LEENV 186_ VDREQ 191_ IDFLA 196_ ARQQF 201_ LSLEQ 206_ ANKGA 211_ PHSSP 216_ ARGTP 221_ AGTTP 226_ GASQA 231_ PKAFN 236_ KPHLA 241_ NGHVV 246_ PIKPQ 251_ VKGVV 256_ REENK 261_ VRAVP 266_ TWASV 271_ QVVDD 276_ PGSLA 281_ SVESP 286_ GTPKE 291_ TPIER 296_ EIRLA 301_ QEREA 306_ DLREQ 311_ RGLRQ 316_ ATDHQ 321_ ELVEI 326_ PTRPL 331_ LTKLS 336_ LITAP 341_ RRERG 346_ RPSLY 351_ VQRDI 356_ VQETQ 361_ REEDH 366_ RREGL 371_ HVGRA 376_ STPDW 381_ VSEGP 386_ QPGLR 391_ RALSS 396_ DSILS 401_ PAPDA 406_ RAADP 411_ APEVR 416_ KVNRI 421_ PPDAY 426_ QPYLS 431_ PGTPQ 436_ LEFSA 441_ FGAFG 446_ KPSSL 451_ STAEA 456_ KAATS 461_ PKATM 466_ SPRHL 471_ SESSG 476_ KPLST 481_ KQEAS 486_ KPPRG 491_ CPQAN 496_ RGVVR 501_ WEYFR 506_ LRPLR 511_ FRAPD 516_ EPQQA 521_ QVPHV 526_ WGWEV 531_ AGAPA 536_ LRLQK 541_ SQSSD 546_ LLERE 551_ RESVL 556_ RREQE 561_ VAEER 566_ RNALF 571_ PEVFS 576_ PTPDE 581_ NSDQN 586_ SRSSS 591_ QASGI 596_ TGSYS 601_ VSESP 606_ FFSPI 611_ HLHSN 616_ VAWTV 621_ EDPVD 626_ SAPPG 631_ QRKKE 636_ QWYAG 641_ INPSD 646_ GINSE 651_ VLEAI 656_ RVTRH 661_ KNAMA 666_ ERWES 671_RIYAS
1: Plays a role in mitotic spindle orientation and mitotic progression. Regulates the distribution of dynactin at the cell cortex in a PLK1-dependent manner, thus stabilizing cortical and astral microtubule attachments required for proper mitotic spindle positioning. May link microtubules to the actin cytospkeleton and focal adhesions. May be required for directed cell migration and centrosome orientation. May also be necessary for proper stacking of the Golgi apparatus