ATP-dependent (S)-NAD(P)H-hydrate dehydratase (EC 4.2.1.93) (ATP-dependent NAD(P)HX dehydratase) (Carbohydrate kinase domain-containing protein) (NAD(P)HX dehydratase)
1_MVTRA 6_ GAGTA 11_ VAGAV 16_ VVALL 21_ SAALA 26_ LYGPP 31_ LDAVL 36_ ERAFS 41_ LRKAH 46_ SIKDM 51_ ENTLQ 56_ LVRNI 61_ IPPLS 66_ STKHK 71_ GQDGR 76_ IGVVG 81_ GCQEY 86_ TGAPY 91_ FAAIS 96_ ALKVG 101_ ADLSH 106_ VFCAS 111_ AAAPV 116_ IKAYS 121_ PELIV 126_ HPVLD 131_ SPNAV 136_ HEVEK 141_ WLPRL 146_ HALVV 151_ GPGLG 156_ RDDAL 161_ LRNVQ 166_ GILEV 171_ SKARD 176_ IPVVI 181_ DADGL 186_ WLVAQ 191_ QPALI 196_ HGYRK 201_ AVLTP 206_ NHVEF 211_ SRLYD 216_ AVLRG 221_ PMDSD 226_ DSHGS 231_ VLRLS 236_ QALGN 241_ VTVVQ 246_ KGERD 251_ ILSNG 256_ QQVLV 261_ CSQEG 266_ SSRRC 271_ GGQGD 276_ LLSGS 281_ LGVLV 286_ HWALL 291_ AGPQK 296_ TNGSS 301_ PLLVA 306_ AFGAC 311_ SLTRQ 316_ CNHQA 321_ FQKHG 326_ RSTTT 331_ SDMIA 336_ EVGAA 341_FSKLF
1: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration