Inactive serine/threonine-protein kinase TEX14 (Protein kinase-like protein SgK307) (Sugen kinase 307) (Testis-expressed sequence 14) (Testis-expressed sequence 14 protein)
1_MSRAV 6_ RLPVP 11_ CPVQL 16_ GTLRN 21_ DSLEA 26_ QLHEY 31_ VKQGN 36_ YVKVK 41_ KILKK 46_ GIYVD 51_ AVNSL 56_ GQTAL 61_ FVAAL 66_ LGLRK 71_ FVDVL 76_ VDYGS 81_ DPNHR 86_ CFDGS 91_ TPVHA 96_ AAFSG 101_ NQWIL 106_ SKLLD 111_ AGGDL 116_ RLHDE 121_ RGQNP 126_ KTWAL 131_ TAGKE 136_ RSTQI 141_ VEFMQ 146_ RCASH 151_ MQAII 156_ QGFSY 161_ DLLKK 166_ IDSPQ 171_ RLVYS 176_ PSWCG 181_ GLVQG 186_ NPNGS 191_ PNRLL 196_ KAGVI 201_ SAQNI 206_ YSFGF 211_ GKAMP 216_ WFQFY 221_ LTGAT 226_ QMAYL 231_ GSLPV 236_ IGEKE 241_ VIQAD 246_ DEPTF 251_ SFFSG 256_ PYMVM 261_ TNLVW 266_ NGSRV 271_ TVKEL 276_ NLPTH 281_ PHCSR 286_ LRLAD 291_ LLIAE 296_ QEHSS 301_ KLRHP 306_ YLLQL 311_ MAVCL 316_ SQDLE 321_ KTRLV 326_ YERIT 331_ IGTLF 336_ SVLHE 341_ RRSQF 346_ PVLHM 351_ EVIVH 356_ LLLQI 361_ SDALR 366_ YLHFQ 371_ GFIHR 376_ SLSSY 381_ AVHII 386_ SPGEA 391_ RLTNL 396_ EYMLE 401_ SEDRG 406_ VQRDL 411_ TRVPL 416_ PTQLY 421_ NWAAP 426_ EVILQ 431_ KAATV 436_ KSDIY 441_ SFSMI 446_ MQEIL 451_ TDDIP 456_ WKGLD 461_ GSVVK 466_ KAVVS 471_ GNYLE 476_ ADVRL 481_ PKPYY 486_ DIVKS 491_ GIHVK 496_ QKDRT 501_ MNLQD 506_ IRYIL 511_ KNDLK 516_ DFTGA 521_ QRTQP 526_ TESPR 531_ VQRYG 536_ LHPDV 541_ NVYLG 546_ LTSEH 551_ PRETP 556_ DMEII 561_ ELKEM 566_ GSQPH 571_ SPRVH 576_ SLFTE 581_ GTLDP 586_ QAPDP 591_ CLMAR 596_ ETQNQ 601_ DAPCP 606_ APFMA 611_ EEASS 616_ PSTGQ 621_ PSLCS 626_ FEINE 631_ IYSGC 636_ LILED 641_ DIEEP 646_ PGAAS 651_ SLEAD 656_ GPNQV 661_ DELKS 666_ MEEEL 671_ DKMER 676_ EACCF 681_ GSEDE 686_ SSSKA 691_ ETEYS 696_ FDDWD 701_ WQNGS 706_ LSSLS 711_ LPEST 716_ REAKS 721_ NLNNM 726_ STTEE 731_ YLISK 736_ CVLDL 741_ KIMQT 746_ IMHEN 751_ DDRLR 756_ NIEQI 761_ LDEVE 766_ MKQKE 771_ QEERM 776_ SLWAT 781_ SREFT 786_ NAYKL 791_ PLAVG 796_ PPSLN 801_ YIPPV 806_ LQLSG 811_ GQKPD 816_ TSGNY 821_ PTLPR 826_ FPRML 831_ PTLCD 836_ PGKQN 841_ TDEQF 846_ QCTQG 851_ AKDSL 856_ ETSRI 861_ QNTSS 866_ QGRPR 871_ ESTAQ 876_ AKATQ 881_ FNSAL 886_ FTLSS 891_ HRQGP 896_ SASPS 901_ CHWDS 906_ TRMSV 911_ EPVSS 916_ EIYNA 921_ ESRNK 926_ DDGKV 931_ HLKWK 936_ MEVKE 941_ MAKKA 946_ ATGQL 951_ TVPPW 956_ HPQSS 961_ LTLES 966_ EAENE 971_ PDALL 976_ QPPIR 981_ SPENT 986_ DWQRV 991_ IEYHR 996_ ENDEP 1001_ RGNGK 1006_ FDKTG 1011_ NNDCD 1016_ SDQHG 1021_ RQPRL 1026_ GSFTS 1031_ IRHPS 1036_ PRQKE 1041_ QPEHS 1046_ EAFQA 1051_ SSDTL 1056_ VAVEK 1061_ SYSHQ 1066_ SMQST 1071_ CSPES 1076_ SEDIT 1081_ DEFLT 1086_ PDGEY 1091_ FYSST 1096_ AQENL 1101_ ALETS 1106_ SPIEE 1111_ DFEGI 1116_ QGAFA 1121_ QPQVS 1126_ GEEKF 1131_ QMRKI 1136_ LGKNA 1141_ EILPR 1146_ SQFQP 1151_ VRSTE 1156_ DEQEE 1161_ TSKES 1166_ PKELK 1171_ EKDIS 1176_ LTDIQ 1181_ DLSSI 1186_ SYEPD 1191_ SSFKE 1196_ ASCKT 1201_ PKINH 1206_ APTSV 1211_ STPLS 1216_ PGSVS 1221_ SAASQ 1226_ YKDCL 1231_ ESITF 1236_ QVKTE 1241_ FASCW 1246_ NSQEF 1251_ IQTLS 1256_ DDFIS 1261_ VRERA 1266_ KKLDS 1271_ LLTSS 1276_ ETPPS 1281_ RLTGL 1286_ KRLSS 1291_ FIGAG 1296_ SPSLV 1301_ KACDS 1306_ SPPHA 1311_ TQRRS 1316_ LPKVE 1321_ AFSQH 1326_ HIDEL 1331_ PPPSQ 1336_ ELLDD 1341_ IELLK 1346_ QQQGS 1351_ STVLH 1356_ ENTAS 1361_ DGGGT 1366_ ANDQR 1371_ HLEEQ 1376_ ETDSK 1381_ KEDSS 1386_ MLLSK 1391_ ETEDL 1396_ GEDTE 1401_ RAHST 1406_ LDEDL 1411_ ERWLQ 1416_ PPEES 1421_ VELQD 1426_ LPKGS 1431_ ERETN 1436_ IKDQK 1441_ VGEEK 1446_ RKRED 1451_ SITPE 1456_ RRKSE 1461_ GVLGT 1466_ SEEDE 1471_ LKSCF 1476_ WKRLG 1481_ WSESS 1486_ RIIVL 1491_DQSDL
1: Required both for the formation of intercellular bridges during meiosis and for kinetochore-microtubule attachment during mitosis. Intercellular bridges are evolutionarily conserved structures that connect differentiating germ cells and are required for spermatogenesis and male fertility. Acts by promoting the conversion of midbodies into intercellular bridges via its interaction with CEP55: interaction with CEP55 inhibits the interaction between CEP55 and PDCD6IP/ALIX and TSG101, blocking cell abscission and leading to transform midbodies into intercellular bridges. Also plays a role during mitosis: recruited to kinetochores by PLK1 during early mitosis and regulates the maturation of the outer kinetochores and microtubule attachment. Has no protein kinase activity in vitro (By similarity)