Extracellular sulfatase Sulf-2 (hSulf-2) (EC 3.1.6.-)
1_MGPPS 6_ LVLCL 11_ LSATV 16_ FSLLG 21_ GSSAF 26_ LSHHR 31_ LKGRF 36_ QRDRR 41_ NIRPN 46_ IILVL 51_ TDDQD 56_ VELGS 61_ MQVMN 66_ KTRRI 71_ MEQGG 76_ AHFIN 81_ AFVTT 86_ PMCCP 91_ SRSSI 96_ LTGKY 101_ VHNHN 106_ TYTNN 111_ ENCSS 116_ PSWQA 121_ QHESR 126_ TFAVY 131_ LNSTG 136_ YRTAF 141_ FGKYL 146_ NEYNG 151_ SYVPP 156_ GWKEW 161_ VGLLK 166_ NSRFY 171_ NYTLC 176_ RNGVK 181_ EKHGS 186_ DYSKD 191_ YLTDL 196_ ITNDS 201_ VSFFR 206_ TSKKM 211_ YPHRP 216_ VLMVI 221_ SHAAP 226_ HGPED 231_ SAPQY 236_ SRLFP 241_ NASQH 246_ ITPSY 251_ NYAPN 256_ PDKHW 261_ IMRYT 266_ GPMKP 271_ IHMEF 276_ TNMLQ 281_ RKRLQ 286_ TLMSV 291_ DDSME 296_ TIYNM 301_ LVETG 306_ ELDNT 311_ YIVYT 316_ ADHGY 321_ HIGQF 326_ GLVKG 331_ KSMPY 336_ EFDIR 341_ VPFYV 346_ RGPNV 351_ EAGCL 356_ NPHIV 361_ LNIDL 366_ APTIL 371_ DIAGL 376_ DIPAD 381_ MDGKS 386_ ILKLL 391_ DTERP 396_ VNRFH 401_ LKKKM 406_ RVWRD 411_ SFLVE 416_ RGKLL 421_ HKRDN 426_ DKVDA 431_ QEENF 436_ LPKYQ 441_ RVKDL 446_ CQRAE 451_ YQTAC 456_ EQLGQ 461_ KWQCV 466_ EDATG 471_ KLKLH 476_ KCKGP 481_ MRLGG 486_ SRALS 491_ NLVPK 496_ YYGQG 501_ SEACT 506_ CDSGD 511_ YKLSL 516_ AGRRK 521_ KLFKK 526_ KYKAS 531_ YVRSR 536_ SIRSV 541_ AIEVD 546_ GRVYH 551_ VGLGD 556_ AAQPR 561_ NLTKR 566_ HWPGA 571_ PEDQD 576_ DKDGG 581_ DFSGT 586_ GGLPD 591_ YSAAN 596_ PIKVT 601_ HRCYI 606_ LENDT 611_ VQCDL 616_ DLYKS 621_ LQAWK 626_ DHKLH 631_ IDHEI 636_ ETLQN 641_ KIKNL 646_ REVRG 651_ HLKKK 656_ RPEEC 661_ DCHKI 666_ SYHTQ 671_ HKGRL 676_ KHRGS 681_ SLHPF 686_ RKGLQ 691_ EKDKV 696_ WLLRE 701_ QKRKK 706_ KLRKL 711_ LKRLQ 716_ NNDTC 721_ SMPGL 726_ TCFTH 731_ DNQHW 736_ QTAPF 741_ WTLGP 746_ FCACT 751_ SANNN 756_ TYWCM 761_ RTINE 766_ THNFL 771_ FCEFA 776_ TGFLE 781_ YFDLN 786_ TDPYQ 791_ LMNAV 796_ NTLDR 801_ DVLNQ 806_ LHVQL 811_ MELRS 816_ CKGYK 821_ QCNPR 826_ TRNMD 831_ LGLKD 836_ GGSYE 841_ QYRQF 846_ QRRKW 851_ PEMKR 856_ PSSKS 861_LGQLW
1: Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity (PubMed:12368295, PubMed:30788513, PubMed:35294879). It can remove sulfate from the C-6 position of glucosamine within specific subregions of intact heparin (PubMed:12368295, PubMed:30788513, PubMed:35294879)