Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1) (Death inducer with SAP domain)
1_MAQFG 6_ GQKNP 11_ PWATQ 16_ FTATA 21_ VSQPA 26_ ALGVQ 31_ QPSLL 36_ GASPT 41_ IYTQQ 46_ TALAA 51_ AGLTT 56_ QTPAN 61_ YQLTQ 66_ TAALQ 71_ QQAAA 76_ AAAAL 81_ QQQYS 86_ QPQQA 91_ LYSVQ 96_ QQLQQ 101_ PQQTL 106_ LTQPA 111_ VALPT 116_ SLSLS 121_ TPQPT 126_ AQITV 131_ SYPTP 136_ RSSQQ 141_ QTQPQ 146_ KQRVF 151_ TGVVT 156_ KLHDT 161_ FGFVD 166_ EDVFF 171_ QLSAV 176_ KGKTP 181_ QVGDR 186_ VLVEA 191_ TYNPN 196_ MPFKW 201_ NAQRI 206_ QTLPN 211_ QNQSQ 216_ TQPLL 221_ KTPPA 226_ VLQPI 231_ APQTT 236_ FGVQT 241_ QPQPQ 246_ SLLQA 251_ QISAA 256_ SITPL 261_ LQTQP 266_ QPLLQ 271_ QPQQK 276_ AGLLQ 281_ PPVRI 286_ VSQPQ 291_ PARRL 296_ DPPSR 301_ FSGRN 306_ DRGDQ 311_ VPNRK 316_ DDRSR 321_ ERERE 326_ RRRSR 331_ ERSPQ 336_ RKRSR 341_ ERSPR 346_ RERER 351_ SPRRV 356_ RRVVP 361_ RYTVQ 366_ FSKFS 371_ LDCPS 376_ CDMME 381_ LRRRY 386_ QNLYI 391_ PSDFF 396_ DAQFT 401_ WVDAF 406_ PLSRP 411_ FQLGN 416_ YCNFY 421_ VMHRE 426_ VESLE 431_ KNMAI 436_ LDPPD 441_ ADHLY 446_ SAKVM 451_ LMASP 456_ SMEDL 461_ YHKSC 466_ ALAED 471_ PQELR 476_ DGFQH 481_ PARLV 486_ KFLVG 491_ MKGKD 496_ EAMAI 501_ GGHWS 506_ PSLDG 511_ PDPEK 516_ DPSVL 521_ IKTAI 526_ RCCKA 531_ LTGID 536_ LSVCT 541_ QWYRF 546_ AEIRY 551_ HRPEE 556_ THKGR 561_ TVPAH 566_ VETVV 571_ LFFPD 576_ VWHCL 581_ PTRSE 586_ WETLS 591_ RGYKQ 596_ QLVEK 601_ LQGER 606_ KEADG 611_ EQDEE 616_ EKDDG 621_ EAKEI 626_ STPTH 631_ WSKLD 636_ PKTMK 641_ VNDLR 646_ KELES 651_ RALSS 656_ KGLKS 661_ QLIAR 666_ LTKQL 671_ KVEEQ 676_ KEEQK 681_ ELEKS 686_ EKEED 691_ EDDDR 696_ KSEDD 701_ KEEEE 706_ RKRQE 711_ EIERQ 716_ RRERR 721_ YILPD 726_ EPAII 731_ VHPNW 736_ AAKSG 741_ KFDCS 746_ IMSLS 751_ VLLDY 756_ RLEDN 761_ KEHSF 766_ EVSLF 771_ AELFN 776_ EMLQR 781_ DFGVR 786_ IYKSL 791_ LSLPE 796_ KEDKK 801_ EKDKK 806_ SKKDE 811_ RKDKK 816_ EERDD 821_ ETDEP 826_ KPKRR 831_ KSGDD 836_ KDKKE 841_ DRDER 846_ KKEDK 851_ RKDDS 856_ KDDDE 861_ TEEDN 866_ NQDEY 871_ DPMEA 876_ EEAED 881_ EEDDR 886_ DEEEM 891_ TKRDD 896_ KRDIN 901_ RYCKE 906_ RPSKD 911_ KEKEK 916_ TQMIT 921_ INRDL 926_ LMAFV 931_ YFDQS 936_ HCGYL 941_ LEKDL 946_ EEILY 951_ TLGLH 956_ LSRAQ 961_ VKKLL 966_ NKVVL 971_ RESCF 976_ YRKLT 981_ DTSKD 986_ EENHE 991_ ESESL 996_ QEDML 1001_ GNRLL 1006_ LPTPT 1011_ VKQES 1016_ KDVEE 1021_ NVGLI 1026_ VYNGA 1031_ MVDVG 1036_ SLLQK 1041_ LEKSE 1046_ KVRAE 1051_ VEQKL 1056_ QLLEE 1061_ KTDED 1066_ EKTIL 1071_ NLENS 1076_ NKSLS 1081_ GELRE 1086_ VKKDL 1091_ SQLQE 1096_ NLKIS 1101_ ENMNL 1106_ QFENQ 1111_ MNKTI 1116_ RNLST 1121_ VMDEI 1126_ HTVLK 1131_ KDNVK 1136_ NEDKD 1141_QKSKE
1: Associates with components of the Mediator and p160 coactivator complexes that play a role as intermediaries transducing regulatory signals from upstream transcriptional activator proteins to basal transcription machinery at the core promoter. Recruited to endogenous nuclear receptor target genes in response to the appropriate hormone. Also functions as a p53 coactivator. May thus play an important role in transcriptional regulation (By similarity). May be involved in apoptosis signaling in the presence of the reinoid CD437. Apoptosis induction involves sequestration of 14-3-3 protein(s) and mediated altered expression of multiple cell cycle regulatory genes including MYC, CCNB1 and CDKN1A. Plays a role in cell cycle progression and/or cell proliferation (PubMed:12816952). In association with CALCOCO1 enhances GATA1- and MED1-mediated transcriptional activation from the gamma-globin promoter during erythroid differentiation of K562 erythroleukemia cells (PubMed:24245781). Can act as a both a coactivator and corepressor of AR-mediated transcription. Contributes to chromatin looping and AR transcription complex assembly by stabilizing AR-GATA2 association on chromatin and facilitating MED1 and RNA polymerase II recruitment to AR-binding sites. May play an important role in the growth and tumorigenesis of prostate cancer cells (PubMed:23887938)