Gene name: SPACA3

Uniprot entry:

Q8IXA5

Protein names:

Sperm acrosome membrane-associated protein 3 (Cancer/testis antigen 54) (CT54) (Lysozyme-like acrosomal sperm-specific secretory protein ALLP-17) (Lysozyme-like protein 3) (Sperm lysozyme-like protein 1) (Sperm protein reactive with antisperm antibodies) (Sperm protein reactive with ASA) [Cleaved into: Sperm acrosome membrane-associated protein 3, membrane form; Sperm acrosome membrane-associated protein 3, processed form]

Protein sequence:

1_MVSAL 6_ RGAPL 11_ IRVHS 16_ SPVSS 21_ PSVSG 26_ PRRLV 31_ SCLSS 36_ QSSAL 41_ SQSGG 46_ GSTSA 51_ AGIEA 56_ RSRAL 61_ RRRWC 66_ PAGIM 71_ LLALV 76_ CLLSC 81_ LLPSS 86_ EAKLY 91_ GRCEL 96_ ARVLH 101_ DFGLD 106_ GYRGY 111_ SLADW 116_ VCLAY 121_ FTSGF 126_ NAAAL 131_ DYEAD 136_ GSTNN 141_ GIFQI 146_ NSRRW 151_ CSNLT 156_ PNVPN 161_ VCRMY 166_ CSDLL 171_ NPNLK 176_ DTVIC 181_ AMKIT 186_ QEPQG 191_ LGYWE 196_ AWRHH 201_ CQGKD 206_LTEWV

Protein annotations

Protein functions:

1: Sperm surface membrane protein that may be involved in sperm-egg plasma membrane adhesion and fusion during fertilization. It could be a potential receptor for the egg oligosaccharide residue N-acetylglucosamine, which is present in the extracellular matrix over the egg plasma membrane. The processed form has no detectable bacteriolytic activity in vitro