Gene name: MRPL41

Uniprot entry:

Q8IXM3

Protein names:

39S ribosomal protein L41, mitochondrial (L41mt) (MRP-L41) (39S ribosomal protein L27 homolog) (Bcl-2-interacting mitochondrial ribosomal protein L41) (Cell proliferation-inducing gene 3 protein) (MRP-L27 homolog) (Mitochondrial large ribosomal subunit protein mL41)

Protein sequence:

1_MGVLA 6_ AAARC 11_ LVRGA 16_ DRMSK 21_ WTSKR 26_ GPRSF 31_ RGRKG 36_ RGAKG 41_ IGFLT 46_ SGWRF 51_ VQIKE 56_ MVPEF 61_ VVPDL 66_ TGFKL 71_ KPYVS 76_ YLAPE 81_ SEETP 86_ LTAAQ 91_ LFSEA 96_ VAPAI 101_ EKDFK 106_ DGTFD 111_ PDNLE 116_ KYGFE 121_ PTQEG 126_ KLFQL 131_YPRNF

Protein annotations

Protein functions:

1: Component of the mitochondrial ribosome large subunit (PubMed:25278503, PubMed:25838379, PubMed:28892042, PubMed:35177605). Also involved in apoptosis and cell cycle (PubMed:16024796, PubMed:16256947). Enhances p53/TP53 stability, thereby contributing to p53/TP53-induced apoptosis in response to growth-inhibitory condition. Enhances p53/TP53 translocation to the mitochondria. Has the ability to arrest the cell cycle at the G1 phase, possibly by stabilizing the CDKN1A and CDKN1B (p27Kip1) proteins (PubMed:16024796)