Dynein regulatory complex subunit 2 (Coiled-coil domain-containing protein 65) (Testis development protein NYD-SP28)
1_MPKKE 6_ KMAKT 11_ PLSDE 16_ KQLLL 21_ FQQKL 26_ LAEEE 31_ MAKKK 36_ ERLLS 41_ QFLKD 46_ KLAKE 51_ EHNSA 56_ LNLNK 61_ INTQW 66_ RTVLR 71_ EVKTR 76_ ELHKD 81_ IEILS 86_ QTFER 91_ VVDCK 96_ DNVIK 101_ SLAKD 106_ LSEAE 111_ EQYAH 116_ ALRSH 121_ LHNVD 126_ QLLAL 131_ QRHRL 136_ SLLEE 141_ SYNME 146_ LEALT 151_ KEFET 156_ ERKTI 161_ IDQHE 166_ KEIHY 171_ LQDIF 176_ MAMEQ 181_ NYIDS 186_ EYESK 191_ LEFQS 196_ MWNDL 201_ KNMNL 206_ EEKHF 211_ LRLHL 216_ ENRVE 221_ DLWRK 226_ FQDVL 231_ KNYTD 236_ ATEDR 241_ KAAFE 246_ TLQVK 251_ DEKSS 256_ KEIEV 261_ QMKKI 266_ QKLQD 271_ AITIS 276_ KGKIM 281_ IHSRE 286_ SEDEN 291_ RYIRN 296_ DKELV 301_ LVQLR 306_ KLKAQ 311_ RTQAR 316_ AASQK 321_ NLVRL 326_ TLESN 331_ ATLKA 336_ LRKIV 341_ DKGEK 346_ ILKLA 351_ EICRK 356_ FETEE 361_ EKVLP 366_ FYSSV 371_ LTPKE 376_ QEGIQ 381_ KNNLE 386_ ELTEE 391_ LTKVM 396_ VDYIG 401_ MENFW 406_ KRYNK 411_ VKLEQ 416_ LSLQH 421_ RRAQL 426_ LDING 431_ KLREM 436_ LKQYL 441_ DGISV 446_ SDEVL 451_ SQLNP 456_ LFIVN 461_ YQSNL 466_ LQPLS 471_ IRIAH 476_PGDKQ
1: Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes (By similarity). Plays a critical role in the assembly of N-DRC and also stabilizes the assembly of multiple inner dynein arms and radial spokes. Coassembles with DRC1 to form a central scaffold needed for assembly of the N-DRC and its attachment to the outer doublet microtubules (PubMed:24094744)