Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2 (EC 2.1.1.296) (Cap methyltransferase 2) (Cap2 2'O-ribose methyltransferase 2) (HMTr2) (MTr2) (FtsJ methyltransferase domain-containing protein 1) (Protein adrift homolog)
1_MSKCR 6_ KTPVQ 11_ QLASP 16_ ASFSP 21_ DILAD 26_ IFELF 31_ AKNFS 36_ YGKPL 41_ NNEWQ 46_ LPDPS 51_ EIFTC 56_ DHTEL 61_ NAFLD 66_ LKNSL 71_ NEVKN 76_ LLSDK 81_ KLDEW 86_ HEHTA 91_ FTNKA 96_ GKIIS 101_ HVRKS 106_ VNAEL 111_ CTQAW 116_ CKFHE 121_ ILCSF 126_ PLIPQ 131_ EAFQN 136_ GKLNS 141_ LHLCE 146_ APGAF 151_ IASLN 156_ HYLKS 161_ HRFPC 166_ HWSWV 171_ ANTLN 176_ PYHEA 181_ NDDLM 186_ MIMDD 191_ RLIAN 196_ TLHWW 201_ YFGPD 206_ NTGDI 211_ MTLKF 216_ LTGLQ 221_ NFISS 226_ MATVH 231_ LVTAD 236_ GSFDC 241_ QGNPG 246_ EQEAL 251_ VSSLH 256_ YCEVV 261_ TALTT 266_ LGNGG 271_ SFVLK 276_ MFTMF 281_ EHCSI 286_ NLMYL 291_ LNCCF 296_ DQVHV 301_ FKPAT 306_ SKAGN 311_ SEVYV 316_ VCLHY 321_ KGREA 326_ IHPLL 331_ SKMTL 336_ NFGTE 341_ MKRKA 346_ LFPHH 351_ VIPDS 356_ FLKRH 361_ EECCV 366_ FFHKY 371_ QLETI 376_ SENIR 381_ LFECM 386_ GKAEQ 391_ EKLNN 396_ LRDCA 401_ IQYFM 406_ QKFQL 411_ KHLSR 416_ NNWLV 421_ KKSSI 426_ GCSTN 431_ TKWFG 436_ QRNKY 441_ FKTYN 446_ ERKML 451_ EALSW 456_ KDKVA 461_ KGYFN 466_ SWAEE 471_ HGVYH 476_ PGQSS 481_ ILEGT 486_ ASNLE 491_ CHLWH 496_ ILEGK 501_ KLPKV 506_ KCSPF 511_ CNGEI 516_ LKTLN 521_ EAIEK 526_ SLGGA 531_ FNLDS 536_ KFRPK 541_ QQYSC 546_ SCHVF 551_ SEELI 556_ FSELC 561_ SLTEC 566_ LQDEQ 571_ VVVPS 576_ NQIKC 581_ LLVGF 586_ STLRN 591_ IKMHI 596_ PLEVR 601_ LLESA 606_ ELTTF 611_ SCSLL 616_ HDGDP 621_ TYQRL 626_ FLDCL 631_ LHSLR 636_ ELHTG 641_ DVMIL 646_ PVLSC 651_ FTRFM 656_ AGLIF 661_ VLHSC 666_ FRFIT 671_ FVCPT 676_ SSDPL 681_ RTCAV 686_ LLCVG 691_ YQDLP 696_ NPVFR 701_ YLQSV 706_ NELLS 711_ TLLNS 716_ DSPQQ 721_ VLQFV 726_ PMEVL 731_ LKGAL 736_ LDFLW 741_ DLNAA 746_ IAKRH 751_ LHFII 756_ QRERE 761_EIINS
1: S-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap2 2'-O-ribose methylation to the 5'-cap structure of mRNAs. Methylates the ribose of the second nucleotide of a m(7)GpppG-capped mRNA and small nuclear RNA (snRNA) (cap0) to produce m(7)GpppRmpNm (cap2). Recognizes a guanosine cap on RNA independently of its N(7) methylation status. Display cap2 methylation on both cap0 and cap1. Displays a preference for cap1 RNAs