Dead end protein homolog 1 (RNA-binding motif, single-stranded-interacting protein 4)
1_MQSKR 6_ DCELW 11_ CERVN 16_ PENKA 21_ ALEAW 26_ VRETG 31_ IRLVQ 36_ VNGQR 41_ KYGGP 46_ PPGWV 51_ GSPPP 56_ AGSEV 61_ FIGRL 66_ PQDVY 71_ EHQLI 76_ PLFQR 81_ VGRLY 86_ EFRLM 91_ MTFSG 96_ LNRGF 101_ AYARY 106_ SSRRG 111_ AQAAI 116_ ATLHN 121_ HPLRP 126_ SCPLL 131_ VCRST 136_ EKCEL 141_ SVDGL 146_ PPNLT 151_ RSALL 156_ LALQP 161_ LGPGL 166_ QEARL 171_ LPSPG 176_ PAPGQ 181_ IALLK 186_ FSSHR 191_ AAAMA 196_ KKALV 201_ EGQSH 206_ LCGEQ 211_ VAVEW 216_ LKPDL 221_ KQRLR 226_ QQLVG 231_ PFLRS 236_ PQPEG 241_ SQLAL 246_ ARDKL 251_ GFQGA 256_ RATLQ 261_ LLCQR 266_ MKLGS 271_ PVFLT 276_ KCLGI 281_ GPAGW 286_ HRFWY 291_ QVVIP 296_ GHPVP 301_ FSGLI 306_ WVVLT 311_ LDGRD 316_ GHEVA 321_ KDAVS 326_ VRLLQ 331_ ALSES 336_ GANLL 341_ WSAGA 346_EAGTM
1: RNA-binding factor that positively regulates gene expression by prohibiting miRNA-mediated gene suppression. Relieves miRNA repression in germline cells (By similarity). Prohibits the function of several miRNAs by blocking the accessibility of target mRNAs. Sequence-specific RNA-binding factor that binds specifically to U-rich regions (URRs) in the 3' untranslated region (3'-UTR) of several mRNAs. Does not bind to miRNAs. May play a role during primordial germ cell (PGC) survival (By similarity). However, does not seem to be essential for PGC migration (By similarity)