Leucine-rich repeat-containing protein 34
1_MAAQP 6_ PRPVG 11_ ERSMG 16_ SSREA 21_ ARAPA 26_ RSPAW 31_ ASTQA 36_ STPGA 41_ ALAVQ 46_ RESPE 51_ SGLQK 56_ HYSNL 61_ CMEKS 66_ QKINP 71_ FILHI 76_ LQEVD 81_ EEIKK 86_ GLAAG 91_ ITLNI 96_ AGNNR 101_ LVPVE 106_ RVTGE 111_ DFWIL 116_ SKILK 121_ NCLYI 126_ NGLDV 131_ GYNLL 136_ CDVGA 141_ YYAAK 146_ LLQKQ 151_ LNLIY 156_ LNLMF 161_ NDIGP 166_ EGGEL 171_ IAKVL 176_ HKNRT 181_ LKYLR 186_ MTGNK 191_ IENKG 196_ GMFFA 201_ AMLQI 206_ NSSLE 211_ KLDLG 216_ DCDLG 221_ MQSVI 226_ AFATV 231_ LTQNQ 236_ AIKAI 241_ NLNRP 246_ ILYSE 251_ QEEST 256_ VHVGR 261_ MLKEN 266_ HCLVA 271_ LHMCK 276_ HDIKN 281_ SGIQQ 286_ LCDAL 291_ YLNSS 296_ LRYLD 301_ VSCNK 306_ ITHDG 311_ MVYLA 316_ DVLKS 321_ NTTLE 326_ VIDLS 331_ FNRIE 336_ NAGAN 341_ YLSET 346_ LTSHN 351_ RSLKA 356_ LSVVS 361_ NNIEG 366_ EGLVA 371_ LSQSM 376_ KTNLT 381_ FSHIY 386_ IWGNK 391_ FDEAT 396_ CIAYS 401_ DLIQM 406_ GCLKP 411_ DNTDV 416_ EPFVV 421_ DGRVY 426_ LAEVS 431_ NGLKK 436_ HYYWT 441_ STYGE 446_ SYDHS 451_ SNAGF 456_ALVPV
1: Highly expressed in stem cells where it may be involved in regulation of pluripotency. In embryonic stem cells (ESCs), important for normal expression of the pluripotency regulators POU5F1/OCT4 and KLF4. Also important for expression of the ectodermal marker gene NES and the endodermal marker gene GATA4. Promotes stem cell proliferation in vitro