Ankyrin repeat domain-containing protein 13A (Protein KE03)
1_MSSAC 6_ DAGDH 11_ YPLHL 16_ LVWKN 21_ DYRQL 26_ EKELQ 31_ GQNVE 36_ AVDPR 41_ GRTLL 46_ HLAVS 51_ LGHLE 56_ SARVL 61_ LRHKA 66_ DVTKE 71_ NRQGW 76_ TVLHE 81_ AVSTG 86_ DPEMV 91_ YTVLQ 96_ HRDYH 101_ NTSMA 106_ LEGVP 111_ ELLQK 116_ ILEAP 121_ DFYVQ 126_ MKWEF 131_ TSWVP 136_ LVSRI 141_ CPNDV 146_ CRIWK 151_ SGAKL 156_ RVDIT 161_ LLGFE 166_ NMSWI 171_ RGRRS 176_ FIFKG 181_ EDNWA 186_ ELMEV 191_ NHDDK 196_ VVTTE 201_ RFDLS 206_ QEMER 211_ LTLDL 216_ MKPKS 221_ REVER 226_ RLTSP 231_ VINTS 236_ LDTKN 241_ IAFER 246_ TKSGF 251_ WGWRT 256_ DKAEV 261_ VNGYE 266_ AKVYT 271_ VNNVN 276_ VITKI 281_ RTEHL 286_ TEEEK 291_ KRYKA 296_ DRNPL 301_ ESLLG 306_ TVEHQ 311_ FGAQG 316_ DLTTE 321_ CATAN 326_ NPTAI 331_ TPDEY 336_ FNEEF 341_ DLKDR 346_ DIGRP 351_ KELTI 356_ RTQKF 361_ KAMLW 366_ MCEEF 371_ PLSLV 376_ EQVIP 381_ IIDLM 386_ ARTSA 391_ HFARL 396_ RDFIK 401_ LEFPP 406_ GFPVK 411_ IEIPL 416_ FHVLN 421_ ARITF 426_ GNVNG 431_ CSTAE 436_ ESVSQ 441_ NVEGT 446_ QADSA 451_ SHITN 456_ FEVDQ 461_ SVFEI 466_ PESYY 471_ VQDNG 476_ RNVHL 481_ QDEDY 486_ EIMQF 491_ AIQQS 496_ LLESS 501_ RSQEL 506_ SGPAS 511_ NGGIS 516_ QTNTY 521_ DAQYE 526_ RAIQE 531_ SLLTS 536_ TEGLC 541_ PSALS 546_ ETSRF 551_ DNDLQ 556_ LAMEL 561_ SAKEL 566_ EEWEL 571_ RLQEE 576_ EAELQ 581_QVLQL
1: Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane