Adhesion G-protein coupled receptor G5 (G-protein coupled receptor 114) (G-protein coupled receptor PGR27)
1_MDHCG 6_ ALFLC 11_ LCLLT 16_ LQNAT 21_ TETWE 26_ ELLSY 31_ MENMQ 36_ VSRGR 41_ SSVFS 46_ SRQLH 51_ QLEQM 56_ LLNTS 61_ FPGYN 66_ LTLQT 71_ PTIQS 76_ LAFKL 81_ SCDFS 86_ GLSLT 91_ SATLK 96_ RVPQA 101_ GGQHA 106_ RGQHA 111_ MQFPA 116_ ELTRD 121_ ACKTR 126_ PRELR 131_ LICIY 136_ FSNTH 141_ FFKDE 146_ NNSSL 151_ LNNYV 156_ LGAQL 161_ SHGHV 166_ NNLRD 171_ PVNIS 176_ FWHNQ 181_ SLEGY 186_ TLTCV 191_ FWKEG 196_ ARKQP 201_ WGGWS 206_ PEGCR 211_ TEQPS 216_ HSQVL 221_ CRCNH 226_ LTYFA 231_ VLMQL 236_ SPALV 241_ PAELL 246_ APLTY 251_ ISLVG 256_ CSISI 261_ VASLI 266_ TVLLH 271_ FHFRK 276_ QSDSL 281_ TRIHM 286_ NLHAS 291_ VLLLN 296_ IAFLL 301_ SPAFA 306_ MSPVP 311_ GSACT 316_ ALAAA 321_ LHYAL 326_ LSCLT 331_ WMAIE 336_ GFNLY 341_ LLLGR 346_ VYNIY 351_ IRRYV 356_ FKLGV 361_ LGWGA 366_ PALLV 371_ LLSLS 376_ VKSSV 381_ YGPCT 386_ IPVFD 391_ SWENG 396_ TGFQN 401_ MSICW 406_ VRSPV 411_ VHSVL 416_ VMGYG 421_ GLTSL 426_ FNLVV 431_ LAWAL 436_ WTLRR 441_ LRERA 446_ DAPSV 451_ RACHD 456_ TVTVL 461_ GLTVL 466_ LGTTW 471_ ALAFF 476_ SFGVF 481_ LLPQL 486_ FLFTI 491_ LNSLY 496_ GFFLF 501_ LWFCS 506_ QRCRS 511_ EAEAK 516_ AQIEA 521_FSSSQ
1: Orphan adhesion G-protein coupled receptor (aGPCR) (PubMed:37673336). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors, such as adenylate cyclase (PubMed:37673336). ADGRG5 is specifically coupled to G(s) G proteins and mediates activation of adenylate cyclase activity (PubMed:37673336)