Matrix metalloproteinase-21 (MMP-21) (EC 3.4.24.-)
1_MLAAS 6_ IFRPT 11_ LLLCW 16_ LAAPW 21_ PTQPE 26_ SLFHS 31_ RDRSD 36_ LEPSP 41_ LRQAK 46_ PIADL 51_ HAAQR 56_ FLSRY 61_ GWSGV 66_ WAAWG 71_ PSPEG 76_ PPETP 81_ KGAAL 86_ AEAVR 91_ RFQRA 96_ NALPA 101_ SGELD 106_ AATLA 111_ AMNRP 116_ RCGVP 121_ DMRPP 126_ PPSAP 131_ PSPPG 136_ PPPRA 141_ RSRRS 146_ PRAPL 151_ SLSRR 156_ GWQPR 161_ GYPDG 166_ GAAQA 171_ FSKRT 176_ LSWRL 181_ LGEAL 186_ SSQLS 191_ VADQR 196_ RIVAL 201_ AFRMW 206_ SEVTP 211_ LDFRE 216_ DLAAP 221_ GAAVD 226_ IKLGF 231_ GRGRH 236_ LGCPR 241_ AFDGS 246_ GQEFA 251_ HAWRL 256_ GDIHF 261_ DDDEH 266_ FTPPT 271_ SDTGI 276_ SLLKV 281_ AVHEI 286_ GHVLG 291_ LPHTY 296_ RTGSI 301_ MQPNY 306_ IPQEP 311_ AFELD 316_ WSDRK 321_ AIQKL 326_ YGSCE 331_ GSFDT 336_ AFDWI 341_ RKERN 346_ QYGEV 351_ MVRFS 356_ TYFFR 361_ NSWYW 366_ LYENR 371_ NNRTR 376_ YGDPI 381_ QILTG 386_ WPGIP 391_ THNID 396_ AFVHI 401_ WTWKR 406_ DERYF 411_ FQGNQ 416_ YWRYD 421_ SDKDQ 426_ ALTED 431_ EQGKS 436_ YPKLI 441_ SEGFP 446_ GIPSP 451_ LDTAF 456_ YDRRQ 461_ KLIYF 466_ FKESL 471_ VFAFD 476_ VNRNR 481_ VLNSY 486_ PKRIT 491_ EVFPA 496_ VIPQN 501_ HPFRN 506_ IDSAY 511_ YSYAY 516_ NSIFF 521_ FKGNA 526_ YWKVV 531_ NDKDK 536_ QQNSW 541_ LPANG 546_ LFPKK 551_ FISEK 556_ WFDVC 561_DVHIS
1: Plays a specialized role in the generation of left-right asymmetry during embryogenesis. May act as a negative regulator of the NOTCH-signaling pathway (PubMed:26429889, PubMed:26437028). Cleaves alpha-1-antitrypsin (PubMed:12617721)