EP300-interacting inhibitor of differentiation 3 (EID-3) (E1A-like inhibitor of differentiation 3) (EID-1-like inhibitor of differentiation 3) (Non-structural maintenance of chromosomes element 4 homolog B) (NS4EB) (Non-SMC element 4 homolog B)
1_MKMDV 6_ SVRAA 11_ GCSDD 16_ LSSGE 21_ ADVDP 26_ KLLEL 31_ TADEE 36_ KCRSI 41_ RRQYR 46_ QLMYC 51_ VRQNR 56_ EDIVS 61_ SANNS 66_ LTEAL 71_ EEANV 76_ LFDGV 81_ SRTRE 86_ AALDA 91_ RFLVM 96_ ASDLG 101_ KEKAK 106_ QLNSD 111_ MNFFN 116_ QLAFC 121_ DFLFL 126_ FVGLN 131_ WMEGD 136_ PDKLS 141_ DCDDS 146_ IALSF 151_ WKAIE 156_ KEATS 161_ WMVKA 166_ ETFHF 171_ VFGSF 176_ KLERS 181_ APKPR 186_ LEHQK 191_ KVRKM 196_ EENGN 201_ MPTKL 206_ QKLDL 211_ SSYPE 216_ ATEKN 221_ VERIL 226_ GLLQT 231_ YFRKY 236_ PDTPV 241_ SYFEF 246_ VIDPN 251_ SFSRT 256_ VENIF 261_ YVSFI 266_ VRDGF 271_ ARIRL 276_ DEDRL 281_ PILEP 286_ MNVNQ 291_ MGEGN 296_ DSSCH 301_ GRKQG 306_ VISLT 311_ LQEWK 316_ NIVAA 321_ FEISE 326_AMITY
1: Tissue-specific component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination and mediates sumoylation of shelterin complex (telosome) components
2: Acts as a repressor of nuclear receptor-dependent transcription possibly by interfering with CREBBP-dependent coactivation. May function as a coinhibitor of other CREBBP/EP300-dependent transcription factors