NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2 (B17.2-like) (B17.2L) (Mimitin) (Myc-induced mitochondrial protein) (MMTN) (NDUFA12-like protein)
1_MGWSQ 6_ DLFRA 11_ LWRSL 16_ SREVK 21_ EHVGT 26_ DQFGN 31_ KYYYI 36_ PQYKN 41_ WRGQT 46_ IREKR 51_ IVEAA 56_ NKKEV 61_ DYEAG 66_ DIPTE 71_ WEAWI 76_ RRTRK 81_ TPPTM 86_ EEILK 91_ NEKHR 96_ EEIKI 101_ KSQDF 106_ YEKEK 111_ LLSKE 116_ TSEEL 121_ LPPPV 126_ QTQIK 131_ GHASA 136_ PYFGK 141_ EEPSV 146_ APSST 151_ GKTFQ 156_ PGSWM 161_PRDGK
1: Acts as a molecular chaperone for mitochondrial complex I assembly (PubMed:16200211, PubMed:19384974). Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (PubMed:16200211, PubMed:27626371). Is involved in the initial steps of cilia formation, including removal of CP110 from the mother centrioles, docking of membrane vesicles to the mother centrioles, and establishment of the transition zone (PubMed:38949024)