Gene name: UBE2J2

Uniprot entry:

Q8N2K1

Protein names:

Ubiquitin-conjugating enzyme E2 J2 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme J2) (Non-canonical ubiquitin-conjugating enzyme 2) (NCUBE-2)

Protein sequence:

1_MSSTS 6_ SKRAP 11_ TTATQ 16_ RLKQD 21_ YLRIK 26_ KDPVP 31_ YICAE 36_ PLPSN 41_ ILEWH 46_ YVVRG 51_ PEMTP 56_ YEGGY 61_ YHGKL 66_ IFPRE 71_ FPFKP 76_ PSIYM 81_ ITPNG 86_ RFKCN 91_ TRLCL 96_ SITDF 101_ HPDTW 106_ NPAWS 111_ VSTIL 116_ TGLLS 121_ FMVEK 126_ GPTLG 131_ SIETS 136_ DFTKR 141_ QLAVQ 146_ SLAFN 151_ LKDKV 156_ FCELF 161_ PEVVE 166_ EIKQK 171_ QKAQD 176_ ELSSR 181_ PQTLP 186_ LPDVV 191_ PDGET 196_ HLVQN 201_ GIQLL 206_ NGHAP 211_ GAVPN 216_ LAGLQ 221_ QANRH 226_ HGLLG 231_ GALAN 236_ LFVIV 241_ GFAAF 246_ AYTVK 251_YVLRS

Protein annotations

Protein functions:

1: Catalyzes the covalent attachment of ubiquitin to other proteins. Seems to function in the selective degradation of misfolded membrane proteins from the endoplasmic reticulum (ERAD) (By similarity). In cooperation with the GATOR2 complex, catalyzes 'Lys-6'-linked ubiquitination of NPRL2 (PubMed:36528027)