Lysoplasmalogenase-like protein TMEM86A (Transmembrane protein 86A)
1_MVSPV 6_ TVVKS 11_ EGPKL 16_ VPFFK 21_ ATCVY 26_ FVLWL 31_ PSSSP 36_ SWVST 41_ LIKCL 46_ PIFCL 51_ WLFLL 56_ AHGLG 61_ FLLAH 66_ PSATR 71_ IFVGL 76_ VFSAV 81_ GDAFL 86_ IWQDQ 91_ GYFVH 96_ GLLMF 101_ AVTHM 106_ FYASA 111_ FGMQP 116_ LALRT 121_ GLVMA 126_ ALSGL 131_ CYALL 136_ YPCLS 141_ GAFTY 146_ LVGVY 151_ VALIG 156_ FMGWR 161_ AMAGL 166_ RLAGA 171_ DWRWT 176_ ELAAG 181_ SGALF 186_ FIISD 191_ LTIAL 196_ NKFCF 201_ PVPYS 206_ RALIM 211_ STYYV 216_ AQMLV 221_ ALSAV 226_ ESREP 231_VEHYR
1: Catalyzes the hydrolysis of the vinyl ether bond of choline or ethanolamine lysoplasmalogens, forming fatty aldehyde and glycerophosphocholine or glycerophosphoethanolamine, respectively and is specific for the sn-2-deacylated (lyso) form of plasmalogen (PubMed:36592658). Plays an important role in lysoplasmalogen metabolism in the adipocyte tissue and macrophages (PubMed:36592658)