Polypeptide N-acetylgalactosaminyltransferase 15 (EC 2.4.1.41) (Polypeptide GalNAc transferase-like protein 2) (GalNAc-T-like protein 2) (pp-GaNTase-like protein 2) (Polypeptide N-acetylgalactosaminyltransferase-like protein 2) (Protein-UDP acetylgalactosaminyltransferase-like protein 2) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase-like protein 2)
1_MLLRK 6_ RYRHR 11_ PCRLQ 16_ FLLLL 21_ LMLGC 26_ VLMMV 31_ AMLHP 36_ PHHTL 41_ HQTVT 46_ AQASK 51_ HSPEA 56_ RYRLD 61_ FGESQ 66_ DWVLE 71_ AEDEG 76_ EEYSP 81_ LEGLP 86_ PFISL 91_ REDQL 96_ LVAVA 101_ LPQAR 106_ RNQSQ 111_ GRRGG 116_ SYRLI 121_ KQPRR 126_ QDKEA 131_ PKRDW 136_ GADED 141_ GEVSE 146_ EEELT 151_ PFSLD 156_ PRGLQ 161_ EALSA 166_ RIPLQ 171_ RALPE 176_ VRHPL 181_ CLQQH 186_ PQDSL 191_ PTASV 196_ ILCFH 201_ DEAWS 206_ TLLRT 211_ VHSIL 216_ DTVPR 221_ AFLKE 226_ IILVD 231_ DLSQQ 236_ GQLKS 241_ ALSEY 246_ VARLE 251_ GVKLL 256_ RSNKR 261_ LGAIR 266_ ARMLG 271_ ATRAT 276_ GDVLV 281_ FMDAH 286_ CECHP 291_ GWLEP 296_ LLSRI 301_ AGDRS 306_ RVVSP 311_ VIDVI 316_ DWKTF 321_ QYYPS 326_ KDLQR 331_ GVLDW 336_ KLDFH 341_ WEPLP 346_ EHVRK 351_ ALQSP 356_ ISPIR 361_ SPVVP 366_ GEVVA 371_ MDRHY 376_ FQNTG 381_ AYDSL 386_ MSLRG 391_ GENLE 396_ LSFKA 401_ WLCGG 406_ SVEIL 411_ PCSRV 416_ GHIYQ 421_ NQDSH 426_ SPLDQ 431_ EATLR 436_ NRVRI 441_ AETWL 446_ GSFKE 451_ TFYKH 456_ SPEAF 461_ SLSKA 466_ EKPDC 471_ MERLQ 476_ LQRRL 481_ GCRTF 486_ HWFLA 491_ NVYPE 496_ LYPSE 501_ PRPSF 506_ SGKLH 511_ NTGLG 516_ LCADC 521_ QAEGD 526_ ILGCP 531_ MVLAP 536_ CSDSR 541_ QQQYL 546_ QHTSR 551_ KEIHF 556_ GSPQH 561_ LCFAV 566_ RQEQV 571_ ILQNC 576_ TEEGL 581_ AIHQQ 586_ HWDFQ 591_ ENGMI 596_ VHILS 601_ GKCME 606_ AVVQE 611_ NNKDL 616_ YLRPC 621_ DGKAR 626_ QQWRF 631_DQINA
1: Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Although it displays a much weaker activity toward all substrates tested compared to GALNT2, it is able to transfer up to seven GalNAc residues to the Muc5AC peptide, suggesting that it can fill vicinal Thr/Ser residues in cooperation with other GALNT proteins. Prefers Muc1a as substrate