Ras-related protein Rab-42
1_MEAEG 6_ CRYQF 11_ RVALL 16_ GDAAV 21_ GKTSL 26_ LRSYV 31_ AGAPG 36_ APEPE 41_ PEPEP 46_ TVGAE 51_ CYRRA 56_ LQLRA 61_ GPRVK 66_ LQLWD 71_ TAGHE 76_ RFRCI 81_ TRSFY 86_ RNVVG 91_ VLLVF 96_ DVTNR 101_ KSFEH 106_ IQDWH 111_ QEVMA 116_ TQGPD 121_ KVIFL 126_ LVGHK 131_ SDLQS 136_ TRCVS 141_ AQEAE 146_ ELAAS 151_ LGMAF 156_ VETSV 161_ KNNCN 166_ VDLAF 171_ DTLAD 176_ AIQQA 181_ LQQGD 186_ IKLEE 191_ GWGGV 196_ RLIHK 201_ TQIPR 206_ SPSRK 211_QHSGP
1: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion (By similarity). The physiological function of RAB42 remains undefined (Probable)