Serine/threonine-protein kinase DCLK2 (EC 2.7.11.1) (CaMK-like CREB regulatory kinase 2) (CL2) (CLICK-II) (CLICK2) (Doublecortin domain-containing protein 3B) (Doublecortin-like and CAM kinase-like 2) (Doublecortin-like kinase 2)
1_MASTR 6_ SIELE 11_ HFEER 16_ DKRPR 21_ PGSRR 26_ GAPSS 31_ SGGSS 36_ SSGPK 41_ GNGLI 46_ PSPAH 51_ SAHCS 56_ FYRTR 61_ TLQAL 66_ SSEKK 71_ AKKAR 76_ FYRNG 81_ DRYFK 86_ GLVFA 91_ ISSDR 96_ FRSFD 101_ ALLIE 106_ LTRSL 111_ SDNVN 116_ LPQGV 121_ RTIYT 126_ IDGSR 131_ KVTSL 136_ DELLE 141_ GESYV 146_ CASNE 151_ PFRKV 156_ DYTKN 161_ INPNW 166_ SVNIK 171_ GGTSR 176_ ALAAA 181_ SSVKS 186_ EVKES 191_ KDFIK 196_ PKLVT 201_ VIRSG 206_ VKPRK 211_ AVRIL 216_ LNKKT 221_ AHSFE 226_ QVLTD 231_ ITEAI 236_ KLDSG 241_ VVKRL 246_ CTLDG 251_ KQVTC 256_ LQDFF 261_ GDDDV 266_ FIACG 271_ PEKFR 276_ YAQDD 281_ FVLDH 286_ SECRV 291_ LKSSY 296_ SRSSA 301_ VKYSG 306_ SKSPG 311_ PSRRS 316_ KSPAS 321_ VNGTP 326_ SSQLS 331_ TPKST 336_ KSSSS 341_ SPTSP 346_ GSFRG 351_ LKQIS 356_ AHGRS 361_ SSNVN 366_ GGPEL 371_ DRCIS 376_ PEGVN 381_ GNRCS 386_ ESSTL 391_ LEKYK 396_ IGKVI 401_ GDGNF 406_ AVVKE 411_ CIDRS 416_ TGKEF 421_ ALKII 426_ DKAKC 431_ CGKEH 436_ LIENE 441_ VSILR 446_ RVKHP 451_ NIIML 456_ VEEME 461_ TATEL 466_ FLVME 471_ LVKGG 476_ DLFDA 481_ ITSST 486_ KYTER 491_ DGSAM 496_ VYNLA 501_ NALRY 506_ LHGLS 511_ IVHRD 516_ IKPEN 521_ LLVCE 526_ YPDGT 531_ KSLKL 536_ GDFGL 541_ ATVVE 546_ GPLYT 551_ VCGTP 556_ TYVAP 561_ EIIAE 566_ TGYGL 571_ KVDIW 576_ AAGVI 581_ TYILL 586_ CGFPP 591_ FRSEN 596_ NLQED 601_ LFDQI 606_ LAGKL 611_ EFPAP 616_ YWDNI 621_ TDSAK 626_ ELISQ 631_ MLQVN 636_ VEARC 641_ TAGQI 646_ LSHPW 651_ VSDDA 656_ SQENN 661_ MQAEV 666_ TGKLK 671_ QHFNN 676_ ALPKQ 681_ NSTTT 686_ GVSVI 691_ MNTAL 696_ DKEGQ 701_ IFCSK 706_ HCQDS 711_ GRPGM 716_ EPISP 721_ VPPSV 726_ EEIPV 731_ PGEAV 736_ PAPTP 741_ PESPT 746_ PHPPP 751_ AAPGG 756_ ERAGT 761_WRRHR
1: Protein kinase with a significantly reduced C(a2+)/CAM affinity and dependence compared to other members of the CaMK family. May play a role in the down-regulation of CRE-dependent gene activation probably by phosphorylation of the CREB coactivator CRTC2/TORC2 and the resulting retention of TORC2 in the cytoplasm (By similarity)