Ubiquitin carboxyl-terminal hydrolase MINDY-1 (EC 3.4.19.12) (Deubiquitinating enzyme MINDY-1) (Protein FAM63A)
1_MEYHQ 6_ PEDPA 11_ PGKAG 16_ TAEAV 21_ IPENH 26_ EVLAG 31_ PDEHP 36_ QDTDA 41_ RDADG 46_ EARER 51_ EPADQ 56_ ALLPS 61_ QCGDN 66_ LESPL 71_ PEASS 76_ APPGP 81_ TLGTL 86_ PEVET 91_ IRACS 96_ MPQEL 101_ PQSPR 106_ TRQPE 111_ PDFYC 116_ VKWIP 121_ WKGEQ 126_ TPIIT 131_ QSTNG 136_ PCPLL 141_ AIMNI 146_ LFLQW 151_ KVKLP 156_ PQKEV 161_ ITSDE 166_ LMAHL 171_ GNCLL 176_ SIKPQ 181_ EKSEG 186_ LQLNF 191_ QQNVD 196_ DAMTV 201_ LPKLA 206_ TGLDV 211_ NVRFT 216_ GVSDF 221_ EYTPE 226_ CSVFD 231_ LLGIP 236_ LYHGW 241_ LVDPQ 246_ SPEAV 251_ RAVGK 256_ LSYNQ 261_ LVERI 266_ ITCKH 271_ SSDTN 276_ LVTEG 281_ LIAEQ 286_ FLETT 291_ AAQLT 296_ YHGLC 301_ ELTAA 306_ AKEGE 311_ LSVFF 316_ RNNHF 321_ STMTK 326_ HKSHL 331_ YLLVT 336_ DQGFL 341_ QEEQV 346_ VWESL 351_ HNVDG 356_ DSCFC 361_ DSDFH 366_ LSHSL 371_ GKGPG 376_ AEGGS 381_ GSPET 386_ QLQVD 391_ QDYLI 396_ ALSLQ 401_ QQQPR 406_ GPLGL 411_ TDLEL 416_ AQQLQ 421_ QEEYQ 426_ QQQAA 431_ QPVRM 436_ RTRVL 441_ SLQGR 446_ GATSG 451_ RPAGE 456_ RRQRP 461_KHESD
1: Hydrolase that can specifically remove 'Lys-48'-linked conjugated ubiquitin from proteins. Has exodeubiquitinase activity and has a preference for long polyubiquitin chains. May play a regulatory role at the level of protein turnover