Calcium/calmodulin-dependent protein kinase kinase 1 (CaM-KK 1) (CaM-kinase kinase 1) (CaMKK 1) (EC 2.7.11.17) (CaM-kinase IV kinase) (Calcium/calmodulin-dependent protein kinase kinase alpha) (CaM-KK alpha) (CaM-kinase kinase alpha) (CaMKK alpha)
1_MEGGP 6_ AVCCQ 11_ DPRAE 16_ LVERV 21_ AAIDV 26_ THLEE 31_ ADGGP 36_ EPTRN 41_ GVDPP 46_ PRARA 51_ ASVIP 56_ GSTSR 61_ LLPAR 66_ PSLSA 71_ RKLSL 76_ QERPA 81_ GSYLE 86_ AQAGP 91_ YATGP 96_ ASHIS 101_ PRAWR 106_ RPTIE 111_ SHHVA 116_ ISDAE 121_ DCVQL 126_ NQYKL 131_ QSEIG 136_ KGAYG 141_ VVRLA 146_ YNESE 151_ DRHYA 156_ MKVLS 161_ KKKLL 166_ KQYGF 171_ PRRPP 176_ PRGSQ 181_ AAQGG 186_ PAKQL 191_ LPLER 196_ VYQEI 201_ AILKK 206_ LDHVN 211_ VVKLI 216_ EVLDD 221_ PAEDN 226_ LYLVF 231_ DLLRK 236_ GPVME 241_ VPCDK 246_ PFSEE 251_ QARLY 256_ LRDVI 261_ LGLEY 266_ LHCQK 271_ IVHRD 276_ IKPSN 281_ LLLGD 286_ DGHVK 291_ IADFG 296_ VSNQF 301_ EGNDA 306_ QLSST 311_ AGTPA 316_ FMAPE 321_ AISDS 326_ GQSFS 331_ GKALD 336_ VWATG 341_ VTLYC 346_ FVYGK 351_ CPFID 356_ DFILA 361_ LHRKI 366_ KNEPV 371_ VFPEE 376_ PEISE 381_ ELKDL 386_ ILKML 391_ DKNPE 396_ TRIGV 401_ PDIKL 406_ HPWVT 411_ KNGEE 416_ PLPSE 421_ EEHCS 426_ VVEVT 431_ EEEVK 436_ NSVRL 441_ IPSWT 446_ TVILV 451_ KSMLR 456_ KRSFG 461_ NPFEP 466_ QARRE 471_ ERSMS 476_ APGNL 481_ LVKEG 486_ FGEGG 491_ KSPEL 496_PGVQE
1: Calcium/calmodulin-dependent protein kinase that belongs to a proposed calcium-triggered signaling cascade involved in a number of cellular processes. Phosphorylates CAMK1, CAMK1D, CAMK1G and CAMK4. Involved in regulating cell apoptosis. Promotes cell survival by phosphorylating AKT1/PKB that inhibits pro-apoptotic BAD/Bcl2-antagonist of cell death