Meiosis-specific with OB domain-containing protein (EC 3.1.-.-)
1_MANSF 6_ AARIF 11_ TTLSD 16_ LQTNM 21_ ANLKV 26_ IGIVI 31_ GKTDV 36_ KGFPD 41_ RKNIG 46_ SERYT 51_ FSFTI 56_ RDSPA 61_ HFVNA 66_ ASWGN 71_ EDYIK 76_ SLSDS 81_ FRVGD 86_ CVIIE 91_ NPLIQ 96_ RKEIE 101_ REEKF 106_ SPATP 111_ SNCKL 116_ LLSEN 121_ HSTVK 126_ VCSSY 131_ EVDTK 136_ LLSLI 141_ HLPVK 146_ ESHDY 151_ YSLGD 156_ IVANG 161_ HSLNG 166_ RIINV 171_ LAAVK 176_ SVGEP 181_ KYFTT 186_ SDRRK 191_ GQRCE 196_ VRLYD 201_ ETESS 206_ FAMTC 211_ WDNES 216_ ILLAQ 221_ SWMPR 226_ ETVIF 231_ ASDVR 236_ INFDK 241_ FRNCM 246_ TATVI 251_ SKTII 256_ TTNPD 261_ IPEAN 266_ ILLNF 271_ IRENK 276_ ETNVL 281_ DDEID 286_ SYFKE 291_ SINLS 296_ TIVDV 301_ YTVEQ 306_ LKGKA 311_ LKNEG 316_ KADPS 321_ YGILY 326_ AYIST 331_ LNIDD 336_ ETTKV 341_ VRNRC 346_ SSCGY 351_ IVNEA 356_ SNMCT 361_ TCNKN 366_ SLDFK 371_ SVFLS 376_ FHVLI 381_ DLTDH 386_ TGTLH 391_ SCSLT 396_ GSVAE 401_ ETLGC 406_ TFVLS 411_ HRARS 416_ GLKIS 421_ VLSCK 426_ LADPT 431_ EASRN 436_LSGQK
1: Single-stranded DNA-binding protein required for homologous recombination in meiosis I. Required for double strand breaks (DSBs) repair and crossover formation and promotion of faithful and complete synapsis. Not required for the initial loading of recombinases but required to maintain a proper number of RAD51 and DMC1 foci after the zygotene stage. May act by ensuring the stabilization of recombinases, which is required for successful homology search and meiotic recombination. Displays Single-stranded DNA 3'-5' exonuclease activity in vitro