CUGBP Elav-like family member 5 (CELF-5) (Bruno-like protein 5) (CUG-BP- and ETR-3-like factor 5) (RNA-binding protein BRUNOL-5)
1_MARLT 6_ ESEAR 11_ RQQQQ 16_ LLQPR 21_ PSPVG 26_ SSGPE 31_ PPGGQ 36_ PDGMK 41_ DLDAI 46_ KLFVG 51_ QIPRH 56_ LDEKD 61_ LKPLF 66_ EQFGR 71_ IYELT 76_ VLKDP 81_ YTGMH 86_ KGCAF 91_ LTYCA 96_ RDSAI 101_ KAQTA 106_ LHEQK 111_ TLPGM 116_ ARPIQ 121_ VKPAD 126_ SESRG 131_ GRDRK 136_ LFVGM 141_ LNKQQ 146_ SEEDV 151_ LRLFQ 156_ PFGVI 161_ DECTV 166_ LRGPD 171_ GSSKG 176_ CAFVK 181_ FSSHT 186_ EAQAA 191_ IHALH 196_ GSQTM 201_ PGASS 206_ SLVVK 211_ FADTD 216_ KERTL 221_ RRMQQ 226_ MVGQL 231_ GILTP 236_ SLTLP 241_ FSPYS 246_ AYAQA 251_ LMQQQ 256_ TTVLS 261_ TSGSY 266_ LSPGV 271_ AFSPC 276_ HIQQI 281_ GAVSL 286_ NGLPA 291_ TPIAP 296_ ASGLH 301_ SPPLL 306_ GTTAV 311_ PGLVA 316_ PITNG 321_ FAGVV 326_ PFPGG 331_ HPALE 336_ TVYAN 341_ GLVPY 346_ PAQSP 351_ TVAET 356_ LHPAF 361_ SGVQQ 366_ YTAMY 371_ PTAAI 376_ TPIAH 381_ SVPQP 386_ PPLLQ 391_ QQQRE 396_ GPEGC 401_ NLFIY 406_ HLPQE 411_ FGDTE 416_ LTQMF 421_ LPFGN 426_ IISSK 431_ VFMDR 436_ ATNQS 441_ KCFGF 446_ VSFDN 451_ PASAQ 456_ AAIQA 461_ MNGFQ 466_ IGMKR 471_ LKVQL 476_KRPKD
1: RNA-binding protein implicated in the regulation of pre-mRNA alternative splicing. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition. Binds to muscle-specific splicing enhancer (MSE) intronic sites flanking the alternative exon 5 of TNNT2 pre-mRNA