Tetra-peptide repeat homeobox protein 1
1_MLSLR 6_ EQQLQ 11_ VWFKN 16_ RRAKL 21_ ARERR 26_ LQQQP 31_ QRVPG 36_ QRGRG 41_ ARAAP 46_ LVPAA 51_ SASAP 56_ QRGPS 61_ GILPA 66_ AEPTI 71_ CSLHQ 76_ AWGGP 81_ GCRAQ 86_ KGIPA 91_ ALSPG 96_ PGPIP 101_ APIPG 106_ PAQIP 111_ GPLPG 116_ SIPGP 121_ IPGPA 126_ QIPSP 131_ IPAPI 136_ PGPIS 141_ GPVQI 146_ PGPFR 151_ GPIPG 156_ PISGP 161_ APIPG 166_ PISGP 171_ FSGPN 176_ PGPIP 181_ GPNPG 186_ PIPGP 191_ ISGPI 196_ PGPIS 201_ VPIPG 206_ PIPGP 211_ ISGPI 216_ SGPNP 221_ GPIPG 226_ PIPGP 231_ ISGPN 236_ PGPIP 241_ GPISG 246_ PNPGL 251_ IPGPI 256_ PGPIS 261_ GPGPI 266_ IGPIP 271_ SPAQI 276_ PGPGR 281_ LQGPG 286_ PILSP 291_ GRMRS 296_ PGSLP 301_ GLAPI 306_ LGPGS 311_ GPGSG 316_ SVPAP 321_ IPGPG 326_ SLPAP 331_ APLWP 336_ QSPDA 341_ SDFLP 346_ DTQLF 351_ PHFTE 356_ LLLPL 361_ DPLEG 366_ SSVST 371_ MTSQY 376_ QEGDD 381_ SMGKK 386_ HSGSQ 391_ PQEEG 396_ GSVNE 401_ NHSGP 406_RLLLD
1: Transcription factor expressed after fertilization required for zygotic genome activation (ZGA), a critical event in early embryonic development during which the developmental control passes from maternally provided mRNAs to the expression of the zygotic genome after fertilization (PubMed:35314832, PubMed:36074823). Binds and activates expression of key ZGA marker genes, such as NANOGNB, ZSCAN4, DUXB, KLF5 and DPPA3 (PubMed:36074823). Binds to regulatory DNA sequences containing a 5'-TAATCC-3' sequence motif (PubMed:36074823)