Cytochrome c oxidase assembly protein COX18, mitochondrial (COX18Hs) (Cytochrome c oxidase assembly protein 18)
1_MLCRL 6_ GGRWL 11_ RPLPA 16_ LQLWA 21_ RDLPL 26_ APVPT 31_ SGAKR 36_ PTLPV 41_ WAVAP 46_ VSAVH 51_ ANGWY 56_ EALAA 61_ SSPVR 66_ VAEEV 71_ LLGVH 76_ AATGL 81_ PWWGS 86_ ILLST 91_ VALRG 96_ AVTLP 101_ LAAYQ 106_ HYILA 111_ KVENL 116_ QPEIK 121_ TIARH 126_ LNQEV 131_ AVRAN 136_ QLGWS 141_ KRDAR 146_ LTYLK 151_ NMRRL 156_ ISELY 161_ VRDNC 166_ HPFKA 171_ TVLVW 176_ IQLPM 181_ WIFMS 186_ FALRN 191_ LSTGA 196_ AHSEG 201_ FSVQE 206_ QLATG 211_ GILWF 216_ PDLTA 221_ PDSTW 226_ ILPIS 231_ VGVIN 236_ LLIVE 241_ ICALQ 246_ KIGMS 251_ RFQTY 256_ ITYFV 261_ RAMSV 266_ LMIPI 271_ AATVP 276_ SSIVL 281_ YWLCS 286_ SFVGL 291_ SQNLL 296_ LRSPG 301_ FRQLC 306_ RIPST 311_ KSDSE 316_ TPYKD 321_ IFAAF 326_NTKFI
1: Mitochondrial membrane insertase required for the translocation of the C-terminus of cytochrome c oxidase subunit II (MT-CO2/COX2) across the mitochondrial inner membrane. Plays a role in MT-CO2/COX2 maturation following the COX20-mediated stabilization of newly synthesized MT-CO2/COX2 protein and before the action of the metallochaperones SCO1/2. Essential for the assembly and stability of the mitochondrial respiratory chain complex IV (also known as cytochrome c oxidase)