Gene name: SLC25A29

Uniprot entry:

Q8N8R3

Protein names:

Mitochondrial basic amino acids transporter (Carnitine/acylcarnitine translocase-like) (CACT-like) (Mitochondrial carnitine/acylcarnitine carrier protein CACL) (Mitochondrial ornithine transporter 3) (Solute carrier family 25 member 29)

Protein sequence:

1_MALDF 6_ LAGCA 11_ GGVAG 16_ VLVGH 21_ PFDTV 26_ KVRLQ 31_ VQSVE 36_ KPQYR 41_ GTLHC 46_ FKSII 51_ KQESV 56_ LGLYK 61_ GLGSP 66_ LMGLT 71_ FINAL 76_ VFGVQ 81_ GNTLR 86_ ALGHD 91_ SPLNQ 96_ FLAGA 101_ AAGAI 106_ QCVIC 111_ CPMEL 116_ AKTRL 121_ QLQDA 126_ GPART 131_ YKGSL 136_ DCLAQ 141_ IYGHE 146_ GLRGV 151_ NRGMV 156_ STLLR 161_ ETPSF 166_ GVYFL 171_ TYDAL 176_ TRALG 181_ CEPGD 186_ RLLVP 191_ KLLLA 196_ GGTSG 201_ IVSWL 206_ STYPV 211_ DVVKS 216_ RLQAD 221_ GLRGA 226_ PRYRG 231_ ILDCV 236_ HQSYR 241_ AEGWR 246_ VFTRG 251_ LASTL 256_ LRAFP 261_ VNAAT 266_ FATVT 271_ VVLTY 276_ ARGEE 281_ AGPEG 286_ EAVPA 291_ APAGP 296_ALAQP

Protein annotations

Protein functions:

1: Mitochondrial transporter of arginine, lysine, homoarginine, methylarginine and, to a much lesser extent, ornithine and histidine (PubMed:19287344, PubMed:24652292). Does not transport carnitine nor acylcarnitines (PubMed:24652292). Functions by both counter-exchange and uniport mechanisms (PubMed:24652292). Plays a physiological role in the import of basic amino acids into mitochondria for mitochondrial protein synthesis and amino acid degradation (PubMed:19287344, PubMed:24652292)