V-type proton ATPase subunit d 2 (V-ATPase subunit d 2) (Vacuolar proton pump subunit d 2)
1_MLEGA 6_ ELYFN 11_ VDHGY 16_ LEGLV 21_ RGCKA 26_ SLLTQ 31_ QDYIN 36_ LVQCE 41_ TLEDL 46_ KIHLQ 51_ TTDYG 56_ NFLAN 61_ HTNPL 66_ TVSKI 71_ DTEMR 76_ KRLCG 81_ EFEYF 86_ RNHSL 91_ EPLST 96_ FLTYM 101_ TCSYM 106_ IDNVI 111_ LLMNG 116_ ALQKK 121_ SVKEI 126_ LGKCH 131_ PLGRF 136_ TEMEA 141_ VNIAE 146_ TPSDL 151_ FNAIL 156_ IETPL 161_ APFFQ 166_ DCMSE 171_ NALDE 176_ LNIEL 181_ LRNKL 186_ YKSYL 191_ EAFYK 196_ FCKNH 201_ GDVTA 206_ EVMCP 211_ ILEFE 216_ ADRRA 221_ FIITL 226_ NSFGT 231_ ELSKE 236_ DRETL 241_ YPTFG 246_ KLYPE 251_ GLRLL 256_ AQAED 261_ FDQMK 266_ NVADH 271_ YGVYK 276_ PLFEA 281_ VGGSG 286_ GKTLE 291_ DVFYE 296_ REVQM 301_ NVLAF 306_ NRQFH 311_ YGVFY 316_ AYVKL 321_ KEQEI 326_ RNIVW 331_ IAECI 336_ SQRHR 341_TKINS
1: Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment (By similarity). May play a role in coupling of proton transport and ATP hydrolysis (By similarity). Regulator of osteoclast fusion and bone formation (By similarity)