Telomere repeats-binding bouquet formation protein 1 (Coiled-coil domain-containing protein 79)
1_MESED 6_ TKKTQ 11_ EMKTD 16_ LNLLL 21_ ECLKY 26_ QMDNA 31_ FSQKE 36_ ALVTI 41_ HSICQ 46_ QNSNA 51_ SVYFR 56_ EIGGL 61_ MFVKN 66_ LAKSS 71_ EHSMV 76_ KEAAL 81_ YTLGA 86_ IAEKN 91_ VYCQQ 96_ TLCTS 101_ ELFED 106_ LTWFL 111_ SNDSN 116_ INLKR 121_ MSVYV 126_ ILVLV 131_ SNNRT 136_ GQTLV 141_ RETGC 146_ ITVLS 151_ RLFRT 156_ VISKH 161_ ELDLS 166_ DKNVF 171_ QSYQL 176_ WSSVC 181_ STLCV 186_ CVNNP 191_ QNDEN 196_ QMFCC 201_ SLFPH 206_ ANEWL 211_ KNCTT 216_ PEIIR 221_ PICSF 226_ IGLTL 231_ ANNTY 236_ VQKYF 241_ VSVGG 246_ LDVLS 251_ QVLMQ 256_ LESDS 261_ HETLS 266_ SAKLA 271_ VVVTK 276_ TVDAC 281_ IADNP 286_ TFGIV 291_ LSKYH 296_ IVSKL 301_ LALLL 306_ HESLD 311_ SGEKF 316_ SIMLT 321_ LGHCT 326_ EDCEE 331_ NQYDL 336_ FKNNG 341_ LPLMI 346_ QALTE 351_ SQNEE 356_ LNKAA 361_ TFVLH 366_ NCKKI 371_ TEKLS 376_ LSLGE 381_ YPFDE 386_ NETQQ 391_ LKDIS 396_ VKENN 401_ LEEHW 406_ RKAKE 411_ ILHRI 416_ EQLER 421_ EGNEE 426_ EIQRE 431_ NYQDN 436_ ISSMN 441_ ISIQN 446_ TWKHL 451_ HADRI 456_ GRGSK 461_ AEDED 466_ KSHSR 471_ QLQSY 476_ KSHGV 481_ MSKAC 486_ TNDDQ 491_ MKTPL 496_ KSANP 501_ VHACY 506_ RESEQ 511_ NKTLY 516_ KAKSS 521_ CNQNL 526_ HEETT 531_ FEKNF 536_ VSQSS 541_ DHVFK 546_ HPVHI 551_ AKNIK 556_ QQLPV 561_ TDPFT 566_ LCSDI 571_ INKEV 576_ VSFLA 581_ TPSCS 586_ EMLTY 591_ RCSGC 596_ IAVEK 601_ SLNSR 606_ NFSKL 611_ LHSCP 616_ YQCDR 621_ HKVIV 626_ EAEDR 631_ YKSEL 636_ RKSLI 641_ CNKKI 646_ LLTPR 651_ RRQRL 656_ SNEST 661_ TPGGI 666_ KKRRI 671_ RKNFT 676_ EEEVN 681_ YLFNG 686_ VKKMG 691_ NHWNS 696_ ILWSF 701_ PFQQG 706_ RKAVD 711_ LAHKY 716_ HKLTK 721_HPTCA
1: Meiosis-specific telomere-associated protein involved in meiotic telomere attachment to the nucleus inner membrane, a crucial step for homologous pairing and synapsis. Component of the MAJIN-TERB1-TERB2 complex, which promotes telomere cap exchange by mediating attachment of telomeric DNA to the inner nuclear membrane and replacement of the protective cap of telomeric chromosomes: in early meiosis, the MAJIN-TERB1-TERB2 complex associates with telomeric DNA and the shelterin/telosome complex. During prophase, the complex matures and promotes release of the shelterin/telosome complex from telomeric DNA. In the MAJIN-TERB1-TERB2 complex, TERB1 probably mediates association with the shelterin/telosome complex via interaction with TERF1, promoting priming telomeric DNA attachment'. Promotes telomere association with the nuclear envelope and deposition of the SUN-KASH/LINC complex. Also recruits cohesin to telomeres to develop structural rigidity