SID1 transmembrane family member 2
1_MFALG 6_ LPFLV 11_ LLVAS 16_ VESHL 21_ GVLGP 26_ KNVSQ 31_ KDAEF 36_ ERTYV 41_ DEVNS 46_ ELVNI 51_ YTFNH 56_ TVTRN 61_ RTEGV 66_ RVSVN 71_ VLNKQ 76_ KGAPL 81_ LFVVR 86_ QKEAV 91_ VSFQV 96_ PLILR 101_ GMFQR 106_ KYLYQ 111_ KVERT 116_ LCQPP 121_ TKNES 126_ EIQFF 131_ YVDVS 136_ TLSPV 141_ NTTYQ 146_ LRVSR 151_ MDDFV 156_ LRTGE 161_ QFSFN 166_ TTAAQ 171_ PQYFK 176_ YEFPE 181_ GVDSV 186_ IVKVT 191_ SNKAF 196_ PCSVI 201_ SIQDV 206_ LCPVY 211_ DLDNN 216_ VAFIG 221_ MYQTM 226_ TKKAA 231_ ITVQR 236_ KDFPS 241_ NSFYV 246_ VVVVK 251_ TEDQA 256_ CGGSL 261_ PFYPF 266_ AEDEP 271_ VDQGH 276_ RQKTL 281_ SVLVS 286_ QAVTS 291_ EAYVS 296_ GMLFC 301_ LGIFL 306_ SFYLL 311_ TVLLA 316_ CWENW 321_ RQKKK 326_ TLLVA 331_ IDRAC 336_ PESGH 341_ PRVLA 346_ DSFPG 351_ SSPYE 356_ GYNYG 361_ SFENV 366_ SGSTD 371_ GLVDS 376_ AGTGD 381_ LSYGY 386_ QGRSF 391_ EPVGT 396_ RPRVD 401_ SMSSV 406_ EEDDY 411_ DTLTD 416_ IDSDK 421_ NVIRT 426_ KQYLY 431_ VADLA 436_ RKDKR 441_ VLRKK 446_ YQIYF 451_ WNIAT 456_ IAVFY 461_ ALPVV 466_ QLVIT 471_ YQTVV 476_ NVTGN 481_ QDICY 486_ YNFLC 491_ AHPLG 496_ NLSAF 501_ NNILS 506_ NLGYI 511_ LLGLL 516_ FLLII 521_ LQREI 526_ NHNRA 531_ LLRND 536_ LCALE 541_ CGIPK 546_ HFGLF 551_ YAMGT 556_ ALMME 561_ GLLSA 566_ CYHVC 571_ PNYTN 576_ FQFDT 581_ SFMYM 586_ IAGLC 591_ MLKLY 596_ QKRHP 601_ DINAS 606_ AYSAY 611_ ACLAI 616_ VIFFS 621_ VLGVV 626_ FGKGN 631_ TAFWI 636_ VFSII 641_ HIIAT 646_ LLLST 651_ QLYYM 656_ GRWKL 661_ DSGIF 666_ RRILH 671_ VLYTD 676_ CIRQC 681_ SGPLY 686_ VDRMV 691_ LLVMG 696_ NVINW 701_ SLAAY 706_ GLIMR 711_ PNDFA 716_ SYLLA 721_ IGICN 726_ LLLYF 731_ AFYII 736_ MKLRS 741_ GERIK 746_ LIPLL 751_ CIVCT 756_ SVVWG 761_ FALFF 766_ FFQGL 771_ STWQK 776_ TPAES 781_ REHNR 786_ DCILL 791_ DFFDD 796_ HDIWH 801_ FLSSI 806_ AMFGS 811_ FLVLL 816_ TLDDD 821_ LDTVQ 826_RDKIY
1: Mediates the translocation of RNA and DNA across the lysosomal membrane during RNA and DNA autophagy (RDA), a process in which RNA or DNA is directly imported into lysosomes in an ATP-dependent manner, and degraded (PubMed:27046251, PubMed:27846365). Involved in the uptake of single-stranded oligonucleotides by living cells, a process called gymnosis (PubMed:28277980). In vitro, mediates the uptake of linear DNA more efficiently than that of circular DNA, but exhibits similar uptake efficacy toward RNA and DNA. Binds long double-stranded RNA (dsRNA) (500 - 700 base pairs), but not dsRNA shorter than 100 bp (By similarity)