Ubiquitin-associated domain-containing protein 2 (UBA domain-containing protein 2) (Phosphoglycerate dehydrogenase-like protein 1)
1_MFTST 6_ GSSGL 11_ YKAPL 16_ SKSLL 21_ LVPSA 26_ LSLLL 31_ ALLLP 36_ HCQKL 41_ FVYDL 46_ HAVKN 51_ DFQIW 56_ RLICG 61_ RIICL 66_ DLKDT 71_ FCSSL 76_ LIYNF 81_ RIFER 86_ RYGSR 91_ KFASF 96_ LLGSW 101_ VLSAL 106_ FDFLL 111_ IEAMQ 116_ YFFGI 121_ TAASN 126_ LPSGF 131_ LAPVF 136_ ALFVP 141_ FYCSI 146_ PRVQV 151_ AQILG 156_ PLSIT 161_ NKTLI 166_ YILGL 171_ QLFTS 176_ GSYIW 181_ IVAIS 186_ GLMSG 191_ LCYDS 196_ KMFQV 201_ HQVLC 206_ IPSWM 211_ AKFFS 216_ WTLEP 221_ IFSSS 226_ EPTSE 231_ ARIGM 236_ GATLD 241_ IQRQQ 246_ RMELL 251_ DRQLM 256_ FSQFA 261_ QGRRQ 266_ RQQQG 271_ GMINW 276_ NRLFP 281_ PLRQR 286_ QNVNY 291_ QGGRQ 296_ SEPAA 301_ PPLEV 306_ SEEQV 311_ ARLME 316_ MGFSR 321_ GDALE 326_ ALRAS 331_ NNDLN 336_VATNF
1: Restricts trafficking of FAF2 from the endoplasmic reticulum to lipid droplets (PubMed:23297223). In association with LMBR1L and E3 ubiquitin-protein ligase AMFR, negatively regulates the canonical Wnt signaling pathway in the lymphocytes by promoting the ubiquitin-mediated degradation of CTNNB1 and Wnt receptors FZD6 and LRP6 (PubMed:31073040)