Transmembrane protein 87A
1_MAAAA 6_ WLQVL 11_ PVILL 16_ LLGAH 21_ PSPLS 26_ FFSAG 31_ PATVA 36_ AADRS 41_ KWHIP 46_ IPSGK 51_ NYFSF 56_ GKILF 61_ RNTTI 66_ FLKFD 71_ GEPCD 76_ LSLNI 81_ TWYLK 86_ SADCY 91_ NEIYN 96_ FKAEE 101_ VELYL 106_ EKLKE 111_ KRGLS 116_ GKYQT 121_ SSKLF 126_ QNCSE 131_ LFKTQ 136_ TFSGD 141_ FMHRL 146_ PLLGE 151_ KQEAK 156_ ENGTN 161_ LTFIG 166_ DKTAM 171_ HEPLQ 176_ TWQDA 181_ PYIFI 186_ VHIGI 191_ SSSKE 196_ SSKEN 201_ SLSNL 206_ FTMTV 211_ EVKGP 216_ YEYLT 221_ LEDYP 226_ LMIFF 231_ MVMCI 236_ VYVLF 241_ GVLWL 246_ AWSAC 251_ YWRDL 256_ LRIQF 261_ WIGAV 266_ IFLGM 271_ LEKAV 276_ FYAEF 281_ QNIRY 286_ KGESV 291_ QGALI 296_ LAELL 301_ SAVKR 306_ SLART 311_ LVIIV 316_ SLGYG 321_ IVKPR 326_ LGVTL 331_ HKVVV 336_ AGALY 341_ LLFSG 346_ MEGVL 351_ RVTGA 356_ QTDLA 361_ SLAFI 366_ PLAFL 371_ DTALC 376_ WWIFI 381_ SLTQT 386_ MKLLK 391_ LRRNI 396_ VKLSL 401_ YRHFT 406_ NTLIL 411_ AVAAS 416_ IVFII 421_ WTTMK 426_ FRIVT 431_ CQSDW 436_ RELWV 441_ DDAIW 446_ RLLFS 451_ MILFV 456_ IMVLW 461_ RPSAN 466_ NQRFA 471_ FSPLS 476_ EEEEE 481_ DEQKE 486_ PMLKE 491_ SFEGM 496_ KMRST 501_ KQEPN 506_ GNSKV 511_ NKAQE 516_ DDLKW 521_ VEENV 526_ PSSVT 531_ DVALP 536_ ALLDS 541_ DEERM 546_ITHFE
1: Potential monoatomic ion channel gated by mechanical force, implicated in normal touch sensitivity through the generation of mechanically activated currents (PubMed:32228863, PubMed:38422143). However, a direct channel activity is debated and an alternative could be that it functions as a chaperone for an unidentified mechanosensitive ion channel (PubMed:32228863, PubMed:36373655). Could also be involved in cell mechanosensitivity regulating cell adhesion and migration (PubMed:32228863). May also be involved in retrograde transport from endosomes to the trans-Golgi network (TGN) (PubMed:26157166)