Gene name: UXS1

Uniprot entry:

Q8NBZ7

Protein names:

UDP-glucuronic acid decarboxylase 1 (EC 4.1.1.35) (UDP-glucuronate decarboxylase 1) (UGD) (UXS-1)

Protein sequence:

1_MVSKA 6_ LLRLV 11_ SAVNR 16_ RRMKL 21_ LLGIA 26_ LLAYV 31_ ASVWG 36_ NFVNM 41_ RSIQE 46_ NGELK 51_ IESKI 56_ EEMVE 61_ PLREK 66_ IRDLE 71_ KSFTQ 76_ KYPPV 81_ KFLSE 86_ KDRKR 91_ ILITG 96_ GAGFV 101_ GSHLT 106_ DKLMM 111_ DGHEV 116_ TVVDN 121_ FFTGR 126_ KRNVE 131_ HWIGH 136_ ENFEL 141_ INHDV 146_ VEPLY 151_ IEVDQ 156_ IYHLA 161_ SPASP 166_ PNYMY 171_ NPIKT 176_ LKTNT 181_ IGTLN 186_ MLGLA 191_ KRVGA 196_ RLLLA 201_ STSEV 206_ YGDPE 211_ VHPQS 216_ EDYWG 221_ HVNPI 226_ GPRAC 231_ YDEGK 236_ RVAET 241_ MCYAY 246_ MKQEG 251_ VEVRV 256_ ARIFN 261_ TFGPR 266_ MHMND 271_ GRVVS 276_ NFILQ 281_ ALQGE 286_ PLTVY 291_ GSGSQ 296_ TRAFQ 301_ YVSDL 306_ VNGLV 311_ ALMNS 316_ NVSSP 321_ VNLGN 326_ PEEHT 331_ ILEFA 336_ QLIKN 341_ LVGSG 346_ SEIQF 351_ LSEAQ 356_ DDPQK 361_ RKPDI 366_ KKAKL 371_ MLGWE 376_ PVVPL 381_ EEGLN 386_ KAIHY 391_ FRKEL 396_ EYQAN 401_ NQYIP 406_ KPKPA 411_RIKKG

Protein annotations

Protein functions:

1: Catalyzes the NAD-dependent decarboxylation of UDP-glucuronic acid to UDP-xylose (PubMed:22810237, PubMed:23656592, PubMed:25521717). Necessary for the biosynthesis of the core tetrasaccharide in glycosaminoglycan biosynthesis (PubMed:22810237, PubMed:23656592, PubMed:25521717)