Gene name: RNF149

Uniprot entry:

Q8NC42

Protein names:

E3 ubiquitin-protein ligase RNF149 (EC 2.3.2.27) (DNA polymerase-transactivated protein 2) (RING finger protein 149) (RING-type E3 ubiquitin transferase RNF149)

Protein sequence:

1_MAWRR 6_ REASV 11_ GARGV 16_ LALAL 21_ LALAL 26_ CVPGA 31_ RGRAL 36_ EWFSA 41_ VVNIE 46_ YVDPQ 51_ TNLTV 56_ WSVSE 61_ SGRFG 66_ DSSPK 71_ EGAHG 76_ LVGVP 81_ WAPGG 86_ DLEGC 91_ APDTR 96_ FFVPE 101_ PGGRG 106_ AAPWV 111_ ALVAR 116_ GGCTF 121_ KDKVL 126_ VAARR 131_ NASAV 136_ VLYNE 141_ ERYGN 146_ ITLPM 151_ SHAGT 156_ GNIVV 161_ IMISY 166_ PKGRE 171_ ILELV 176_ QKGIP 181_ VTMTI 186_ GVGTR 191_ HVQEF 196_ ISGQS 201_ VVFVA 206_ IAFIT 211_ MMIIS 216_ LAWLI 221_ FYYIQ 226_ RFLYT 231_ GSQIG 236_ SQSHR 241_ KETKK 246_ VIGQL 251_ LLHTV 256_ KHGEK 261_ GIDVD 266_ AENCA 271_ VCIEN 276_ FKVKD 281_ IIRIL 286_ PCKHI 291_ FHRIC 296_ IDPWL 301_ LDHRT 306_ CPMCK 311_ LDVIK 316_ ALGYW 321_ GEPGD 326_ VQEMP 331_ APESP 336_ PGRDP 341_ AANLS 346_ LALPD 351_ DDGSD 356_ DSSPP 361_ SASPA 366_ ESEPQ 371_ CDPSF 376_ KGDAG 381_ ENTAL 386_ LEAGR 391_SDSRH

Protein annotations

Protein functions:

1: E3 ubiquitin-protein ligase. Ubiquitinates BRAF, inducing its proteasomal degradation