Reticulophagy regulator 2
1_MASGG 6_ GGGNT 11_ GAGGG 16_ PGMGL 21_ SLGLG 26_ LGLSL 31_ GMSEA 36_ TSEAE 41_ EEAAT 46_ AEAVG 51_ RLATT 56_ LWLRL 61_ RGWEA 66_ VLAAA 71_ QRLLV 76_ WEKPL 81_ HSLVT 86_ AAALN 91_ GLFWL 96_ LSSSS 101_ LRPFF 106_ LLSVS 111_ LLAYF 116_ LLDLW 121_ QPRFL 126_ PDVSA 131_ SSPEE 136_ PHSDS 141_ EGAGS 146_ GARPH 151_ LLSVP 156_ ELCRY 161_ LAESW 166_ LTFQI 171_ HLQEL 176_ LQYKR 181_ QNPAQ 186_ FCVRV 191_ CSGCA 196_ VLAVL 201_ GHYVP 206_ GIMIS 211_ YIVLL 216_ SILLW 221_ PLVVY 226_ HELIQ 231_ RMYTR 236_ LEPLL 241_ MQLDY 246_ SMKAE 251_ ANALH 256_ HKHDK 261_ RKRQG 266_ KNAPP 271_ GGDEP 276_ LAETE 281_ SESEA 286_ ELAGF 291_ SPVVD 296_ VKKTA 301_ LALAI 306_ TDSEL 311_ SDEEA 316_ SILES 321_ GGFSV 326_ SRATT 331_ PQLTD 336_ VSEDL 341_ DQQSL 346_ PSEPE 351_ ETLSR 356_ DLGEG 361_ EEGEL 366_ APPED 371_ LLGRP 376_ QALSR 381_ QALDS 386_ EEEEE 391_ DVAAK 396_ ETLLR 401_ LSSPL 406_ HFVNT 411_ HFNGA 416_ GSPPD 421_ GVKCS 426_ PGGPV 431_ ETLSP 436_ ETVSG 441_ GLTAL 446_ PGTLS 451_ PPLCL 456_ VGSDP 461_ APSPS 466_ ILPPV 471_ PQDSP 476_ QPLPA 481_ PEEEE 486_ ALTTE 491_ DFELL 496_ DQGEL 501_ EQLNA 506_ ELGLE 511_ PETPP 516_ KPPDA 521_ PPLGP 526_ DIHSL 531_ VQSDQ 536_EAQAV
1: Endoplasmic reticulum (ER)-anchored autophagy regulator which exists in an inactive state under basal conditions but is activated following cellular stress (PubMed:34338405). When activated, induces ER fragmentation and mediates ER delivery into lysosomes through sequestration into autophagosomes via interaction with ATG8 family proteins (PubMed:34338405). Required for collagen quality control in a LIR motif-independent manner (By similarity)