Polypeptide N-acetylgalactosaminyltransferase 11 (EC 2.4.1.41) (Polypeptide GalNAc transferase 11) (GalNAc-T11) (pp-GaNTase 11) (Protein-UDP acetylgalactosaminyltransferase 11) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 11)
1_MGSVT 6_ VRYFC 11_ YGCLF 16_ TSATW 21_ TVLLF 26_ VYFNF 31_ SEVTQ 36_ PLKNV 41_ PVKGS 46_ GPHGP 51_ SPKKF 56_ YPRFT 61_ RGPSR 66_ VLEPQ 71_ FKANK 76_ IDDVI 81_ DSRVE 86_ DPEEG 91_ HLKFS 96_ SELGM 101_ IFNER 106_ DQELR 111_ DLGYQ 116_ KHAFN 121_ MLISD 126_ RLGYH 131_ RDVPD 136_ TRNAA 141_ CKEKF 146_ YPPDL 151_ PAASV 156_ VICFY 161_ NEAFS 166_ ALLRT 171_ VHSVI 176_ DRTPA 181_ HLLHE 186_ IILVD 191_ DDSDF 196_ DDLKG 201_ ELDEY 206_ VQKYL 211_ PGKIK 216_ VIRNT 221_ KREGL 226_ IRGRM 231_ IGAAH 236_ ATGEV 241_ LVFLD 246_ SHCEV 251_ NVMWL 256_ QPLLA 261_ AIRED 266_ RHTVV 271_ CPVID 276_ IISAD 281_ TLAYS 286_ SSPVV 291_ RGGFN 296_ WGLHF 301_ KWDLV 306_ PLSEL 311_ GRAEG 316_ ATAPI 321_ KSPTM 326_ AGGLF 331_ AMNRQ 336_ YFHEL 341_ GQYDS 346_ GMDIW 351_ GGENL 356_ EISFR 361_ IWMCG 366_ GKLFI 371_ IPCSR 376_ VGHIF 381_ RKRRP 386_ YGSPE 391_ GQDTM 396_ THNSL 401_ RLAHV 406_ WLDEY 411_ KEQYF 416_ SLRPD 421_ LKTKS 426_ YGNIS 431_ ERVEL 436_ RKKLG 441_ CKSFK 446_ WYLDN 451_ VYPEM 456_ QISGS 461_ HAKPQ 466_ QPIFV 471_ NRGPK 476_ RPKVL 481_ QRGRL 486_ YHLQT 491_ NKCLV 496_ AQGRP 501_ SQKGG 506_ LVVLK 511_ ACDYS 516_ DPNQI 521_ WIYNE 526_ EHELV 531_ LNSLL 536_ CLDMS 541_ ETRSS 546_ DPPRL 551_ MKCHG 556_ SGGSQ 561_ QWTFG 566_ KNNRL 571_ YQVSV 576_ GQCLR 581_ AVDPL 586_ GQKGS 591_ VAMAI 596_ CDGSS 601_SQQWH
1: Polypeptide N-acetylgalactosaminyltransferase that catalyzes the initiation of protein O-linked glycosylation and is involved in left/right asymmetry by mediating O-glycosylation of NOTCH1. O-glycosylation of NOTCH1 promotes activation of NOTCH1, modulating the balance between motile and immotile (sensory) cilia at the left-right organiser (LRO). Polypeptide N-acetylgalactosaminyltransferases catalyze the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Displays the same enzyme activity toward MUC1, MUC4, and EA2 than GALNT1. Not involved in glycosylation of erythropoietin (EPO)