Cyclin-Y (Cyc-Y) (Cyclin box protein 1) (Cyclin fold protein 1) (cyclin-X)
1_MGNTT 6_ SCCVS 11_ SSPKL 16_ RRNAH 21_ SRLES 26_ YRPDT 31_ DLSRE 36_ DTGCN 41_ LQHIS 46_ DRENI 51_ DDLNM 56_ EFNPS 61_ DHPRA 66_ STIFL 71_ SKSQT 76_ DVREK 81_ RKSLF 86_ INHHP 91_ PGQIA 96_ RKYSS 101_ CSTIF 106_ LDDST 111_ VSQPN 116_ LKYTI 121_ KCVAL 126_ AIYYH 131_ IKNRD 136_ PDGRM 141_ LLDIF 146_ DENLH 151_ PLSKS 156_ EVPPD 161_ YDKHN 166_ PEQKQ 171_ IYRFV 176_ RTLFS 181_ AAQLT 186_ AECAI 191_ VTLVY 196_ LERLL 201_ TYAEI 206_ DICPA 211_ NWKRI 216_ VLGAI 221_ LLASK 226_ VWDDQ 231_ AVWNV 236_ DYCQI 241_ LKDIT 246_ VEDMN 251_ ELERQ 256_ FLELL 261_ QFNIN 266_ VPSSV 271_ YAKYY 276_ FDLRS 281_ LAEAN 286_ NLSFP 291_ LEPLS 296_ RERAH 301_ KLEAI 306_ SRLCE 311_ DKYKD 316_ LRRSA 321_ RKRSA 326_ SADNL 331_ TLPRW 336_SPAII
1: Positive regulatory subunit of the cyclin-dependent kinases CDK14/PFTK1 and CDK16. Acts as a cell-cycle regulator of Wnt signaling pathway during G2/M phase by recruiting CDK14/PFTK1 to the plasma membrane and promoting phosphorylation of LRP6, leading to the activation of the Wnt signaling pathway. Recruits CDK16 to the plasma membrane. Isoform 3 might play a role in the activation of MYC-mediated transcription