ATP-dependent RNA helicase TDRD9 (EC 3.6.4.13) (Tudor domain-containing protein 9)
1_MLRKL 6_ TIEQI 11_ NDWFT 16_ IGKTV 21_ TNVEL 26_ LGAPP 31_ AFPAG 36_ AAREE 41_ VQRQD 46_ VAPGA 51_ GPAAQ 56_ APALA 61_ QAPAR 66_ PAAAF 71_ ERSLS 76_ QRSSE 81_ VEYIN 86_ KYRQL 91_ EAQEL 96_ DVCRS 101_ VQPTS 106_ GPGPR 111_ PSLAK 116_ LSSVT 121_ CIPGT 126_ TYKYP 131_ DLPIS 136_ RYKEE 141_ VVSLI 146_ ESNSV 151_ VIIHG 156_ ATGSG 161_ KSTQL 166_ PQYIL 171_ DHYVQ 176_ RSAYC 181_ SIVVT 186_ QPRKI 191_ GASSI 196_ ARWIS 201_ KERAW 206_ TLGGV 211_ VGYQV 216_ GLEKI 221_ ATEDT 226_ RLIYM 231_ TTGVL 236_ LQKIV 241_ SAKSL 246_ MEFTH 251_ IIIDE 256_ VHERT 261_ EEMDF 266_ LLLVV 271_ RKLLR 276_ TNSRF 281_ VKVVL 286_ MSATI 291_ SCKEF 296_ ADYFA 301_ VPVQN 306_ KMNPA 311_ YIFEV 316_ EGKPH 321_ SVEEY 326_ YLNDL 331_ EHIHH 336_ SKLSP 341_ HLLEE 346_ PVITK 351_ DIYEV 356_ AVSLI 361_ QMFDD 366_ LDMKE 371_ SGNKA 376_ WSGAQ 381_ FVLER 386_ SSVLV 391_ FLPGL 396_ GEINY 401_ MHELL 406_ TSLVH 411_ KRLQV 416_ YPLHS 421_ SVALE 426_ EQNNV 431_ FLSPV 436_ PGYRK 441_ IILST 446_ NIAES 451_ SVTVP 456_ DVKYV 461_ IDFCL 466_ TRTLV 471_ CDEDT 476_ NYQSL 481_ RLSWA 486_ SKTSC 491_ NQRKG 496_ RAGRV 501_ SRGYC 506_ YRLVH 511_ KDFWD 516_ NSIPD 521_ HVVPE 526_ MLRCP 531_ LGSTI 536_ LKVKL 541_ LDMGE 546_ PRALL 551_ ATALS 556_ PPGLS 561_ DIERT 566_ ILLLK 571_ EVGAL 576_ AVSGQ 581_ REDEN 586_ PHDGE 591_ LTFLG 596_ RVLAQ 601_ LPVNQ 606_ QLGKL 611_ IVLGH 616_ VFGCL 621_ DECLI 626_ IAAAL 631_ SLKNF 636_ FAMPF 641_ RQHLD 646_ GYRNK 651_ VNFSG 656_ SSKSD 661_ CIALV 666_ EAFKT 671_ WKACR 676_ QTGEL 681_ RYPKD 686_ ELNWG 691_ RLNYI 696_ QIKRI 701_ REVAE 706_ LYEEL 711_ KTRIS 716_ QFNMH 721_ VDSRR 726_ PVMDQ 731_ EYIYK 736_ QRFIL 741_ QVVLA 746_ GAFYP 751_ NYFTF 756_ GQPDE 761_ EMAVR 766_ ELAGK 771_ DPKTT 776_ VVLKH 781_ IPPYG 786_ FLYYK 791_ QLQSL 796_ FRQCG 801_ QVKSI 806_ VFDGA 811_ KAFVE 816_ FSRNP 821_ TERFK 826_ TLPAV 831_ YMAIK 836_ MSQLK 841_ VSLEL 846_ SVHSA 851_ EEIEG 856_ KVQGM 861_ NVSKL 866_ RNTRV 871_ NVDFQ 876_ KQTVD 881_ PMQVS 886_ FNTSD 891_ RSQTV 896_ TDLLL 901_ TIDVT 906_ EVVEV 911_ GHFWG 916_ YRIDE 921_ NNSEI 926_ LKKLT 931_ AEINQ 936_ LTLVP 941_ LPTHP 946_ HPDLV 951_ CLAPF 956_ ADFDK 961_ QRYFR 966_ AQVLY 971_ VSGNS 976_ AEVFF 981_ VDYGN 986_ KSHVD 991_ LHLLM 996_ EIPCQ 1001_ FLELP 1006_ FQALE 1011_ FKICK 1016_ MRPSA 1021_ KSLVC 1026_ GKHWS 1031_ DGASQ 1036_ WFASL 1041_ VSGCT 1046_ LLVKV 1051_ FSVVH 1056_ SVLHV 1061_ DVYQY 1066_ SGVQD 1071_ AINIR 1076_ DVLIQ 1081_ QGYAE 1086_ LTEES 1091_ YESKQ 1096_ SHEVL 1101_ KGLFS 1106_ KSVEN 1111_ MTDGS 1116_ VPFPM 1121_ KDDEK 1126_ YLIRI 1131_ LLESF 1136_ STNKL 1141_ GTPNC 1146_ KAELH 1151_ GPFNP 1156_ YELKC 1161_ HSLTR 1166_ ISKFR 1171_ CVWIE 1176_ KESIN 1181_ SVIIS 1186_ DAPED 1191_ LHQRM 1196_ LVAAS 1201_ LSINA 1206_ TGSTM 1211_ LLRET 1216_ SLMPH 1221_ IPGLP 1226_ ALLSM 1231_ LFAPV 1236_ IELRI 1241_ DQNGK 1246_ YYTGV 1251_ LCGLG 1256_ WNPAT 1261_ GASIL 1266_ PEHDM 1271_ ELAFD 1276_ VQFSV 1281_ EDVVE 1286_ VNILR 1291_ AAINK 1296_ LVCDG 1301_ PNGCK 1306_ CLGPE 1311_ RVAQL 1316_ QDIAR 1321_ QKLLG 1326_ LFCQS 1331_ KPREK 1336_ IVPKW 1341_ HEKPY 1346_ EWNQV 1351_ DPKLV 1356_ MEQAD 1361_ RESSR 1366_ GKNTF 1371_ LYQLH 1376_KLVVL
1: ATP-binding RNA helicase required during spermatogenesis (PubMed:28536242). Required to repress transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Acts downstream of piRNA biogenesis: exclusively required for transposon silencing in the nucleus, suggesting that it acts as a nuclear effector in the nucleus together with PIWIL4