Structural maintenance of chromosomes protein 1B (SMC protein 1B) (SMC-1-beta) (SMC-1B)
1_MAHLE 6_ LLLVE 11_ NFKSW 16_ RGRQV 21_ IGPFR 26_ RFTCI 31_ IGPNG 36_ SGKSN 41_ VMDAL 46_ SFVMG 51_ EKIAN 56_ LRVKN 61_ IQELI 66_ HGAHI 71_ GKPIS 76_ SSASV 81_ KIIYV 86_ EESGE 91_ EKTFA 96_ RIIRG 101_ GCSEF 106_ RFNDN 111_ LVSRS 116_ VYIAE 121_ LEKIG 126_ IIVKA 131_ QNCLV 136_ FQGTV 141_ ESISV 146_ KKPKE 151_ RTQFF 156_ EEIST 161_ SGELI 166_ GEYEE 171_ KKRKL 176_ QKAEE 181_ DAQFN 186_ FNKKK 191_ NIAAE 196_ RRQAK 201_ LEKEE 206_ AERYQ 211_ SLLEE 216_ LKMNK 221_ IQLQL 226_ FQLYH 231_ NEKKI 236_ HLLNT 241_ KLEHV 246_ NRDLS 251_ VKRES 256_ LSHHE 261_ NIVKA 266_ RKKEH 271_ GMLTR 276_ QLQQT 281_ EKELK 286_ SVETL 291_ LNQKR 296_ PQYIK 301_ AKENT 306_ SHHLK 311_ KLDVA 316_ KKSIK 321_ DSEKQ 326_ CSKQE 331_ DDIKA 336_ LETEL 341_ ADLDA 346_ AWRSF 351_ EKQIE 356_ EEILH 361_ KKRDI 366_ ELEAS 371_ QLDRY 376_ KELKE 381_ QVRKK 386_ VATMT 391_ QQLEK 396_ LQWEQ 401_ KTDEE 406_ RLAFE 411_ KRRHG 416_ EVQGN 421_ LKQIK 426_ EQIED 431_ HKKRI 436_ EKLEE 441_ YTKTC 446_ MDCLK 451_ EKKQQ 456_ EETLV 461_ DEIEK 466_ TKSRM 471_ SEFNE 476_ ELNLI 481_ RSELQ 486_ NAGID 491_ THEGK 496_ RQQKR 501_ AEVLE 506_ HLKRL 511_ YPDSV 516_ FGRLF 521_ DLCHP 526_ IHKKY 531_ QLAVT 536_ KVFGR 541_ FITAI 546_ VVASE 551_ KVAKD 556_ CIRFL 561_ KEERA 566_ EPETF 571_ LALDY 576_ LDIKP 581_ INERL 586_ RELKG 591_ CKMVI 596_ DVIKT 601_ QFPQL 606_ KKVIQ 611_ FVCGN 616_ GLVCE 621_ TMEEA 626_ RHIAL 631_ SGPER 636_ QKTVA 641_ LDGTL 646_ FLKSG 651_ VISGG 656_ SSDLK 661_ YKARC 666_ WDEKE 671_ LKNLR 676_ DRRSQ 681_ KIQEL 686_ KGLMK 691_ TLRKE 696_ TDLKQ 701_ IQTLI 706_ QGTQT 711_ RLKYS 716_ QNELE 721_ MIKKK 726_ HLVAF 731_ YQEQS 736_ QLQSE 741_ LLNIE 746_ SQCIM 751_ LSEGI 756_ KERQR 761_ RIKEF 766_ QEKID 771_ KVEDD 776_ IFQHF 781_ CEEIG 786_ VENIR 791_ EFENK 796_ HVKRQ 801_ QEIDQ 806_ KRYFY 811_ KKMLT 816_ RLNVQ 821_ LEYSR 826_ SHLKK 831_ KLNKI 836_ NTLKE 841_ TIQKG 846_ SEDID 851_ HLKKA 856_ EENCL 861_ QTVNE 866_ LMAKQ 871_ QQLKD 876_ IRVTQ 881_ NSSAE 886_ KVQTQ 891_ IEEER 896_ KKFLA 901_ VDREV 906_ GKLQK 911_ EVVSI 916_ QTSLE 921_ QKRLE 926_ KHNLL 931_ LDCKV 936_ QDIEI 941_ ILLSG 946_ SLDDI 951_ IEVEM 956_ GTEAE 961_ STQAT 966_ IDIYE 971_ KEEAF 976_ EIDYS 981_ SLKED 986_ LKALQ 991_ SDQEI 996_ EAHLR 1001_ LLLQQ 1006_ VASQE 1011_ DILLK 1016_ TAAPN 1021_ LRALE 1026_ NLKTV 1031_ RDKFQ 1036_ ESTDA 1041_ FEASR 1046_ KEARL 1051_ CRQEF 1056_ EQVKK 1061_ RRYDL 1066_ FTQCF 1071_ EHVSI 1076_ SIDQI 1081_ YKKLC 1086_ RNNSA 1091_ QAFLS 1096_ PENPE 1101_ EPYLE 1106_ GISYN 1111_ CVAPG 1116_ KRFMP 1121_ MDNLS 1126_ GGEKC 1131_ VAALA 1136_ LLFAV 1141_ HSFRP 1146_ APFFV 1151_ LDEVD 1156_ AALDN 1161_ TNIGK 1166_ VSSYI 1171_ KEQTQ 1176_ DQFQM 1181_ IVISL 1186_ KEEFY 1191_ SRADA 1196_ LIGIY 1201_ PEYDD 1206_ CMFSR 1211_ VLTLD 1216_ LSQYP 1221_ DTEGQ 1226_ESSKR
1: Meiosis-specific component of cohesin complex. Required for the maintenance of meiotic cohesion, but not, or only to a minor extent, for its establishment. Contributes to axial element (AE) formation and the organization of chromatin loops along the AE. Plays a key role in synapsis, recombination and chromosome movements. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The meiosis-specific cohesin complex probably replaces mitosis specific cohesin complex when it dissociates from chromatin during prophase I (By similarity)