Trinucleotide repeat-containing gene 6A protein (CAG repeat protein 26) (EMSY interactor protein) (GW182 autoantigen) (Protein GW1) (Glycine-tryptophan protein of 182 kDa)
1_MRELE 6_ AKATK 11_ DVERN 16_ LSRDL 21_ VQEEE 26_ QLMEE 31_ KKKKK 36_ DDKKK 41_ KEAAQ 46_ KKATE 51_ QKIKV 56_ PEQIK 61_ PSVSQ 66_ PQPAN 71_ SNNGT 76_ STATS 81_ TNNNA 86_ KRATA 91_ NNQQP 96_ QQQQQ 101_ QQQPQ 106_ QQQPQ 111_ QQPQP 116_ QPQQQ 121_ QPQQQ 126_ PQALP 131_ RYPRE 136_ VPPRF 141_ RHQEH 146_ KQLLK 151_ RGQHF 156_ PVIAA 161_ NLGSA 166_ VKVLN 171_ SQSES 176_ SALTN 181_ QQPQN 186_ NGEVQ 191_ NSKNQ 196_ SDINH 201_ STSGS 206_ HYENS 211_ QRGPV 216_ SSTSD 221_ SSTNC 226_ KNAVV 231_ SDLSE 236_ KEAWP 241_ SAPGS 246_ DPELA 251_ SECMD 256_ ADSAS 261_ SSESE 266_ RNITI 271_ MASGN 276_ TGGEK 281_ DGLRN 286_ STGLG 291_ SQNKF 296_ VVGSS 301_ SNNVG 306_ HGSST 311_ GPWGF 316_ SHGAI 321_ ISTCQ 326_ VSVDA 331_ PESKS 336_ ESSNN 341_ RMNAW 346_ GTVSS 351_ SSNGG 356_ LNPST 361_ LNSAS 366_ NHGAW 371_ PVLEN 376_ NGLAL 381_ KGPVG 386_ SGSSG 391_ INIQC 396_ STIGQ 401_ MPNNQ 406_ SINSK 411_ VSGGS 416_ THGTW 421_ GSLQE 426_ TCESE 431_ VSGTQ 436_ KVSFS 441_ GQPQN 446_ ITTEM 451_ TGPNN 456_ TTNFM 461_ TSSLP 466_ NSGSV 471_ QNNEL 476_ PSSNT 481_ GAWRV 486_ STMNH 491_ PQMQA 496_ PSGMN 501_ GTSLS 506_ HLSNG 511_ ESKSG 516_ GSYGT 521_ TWGAY 526_ GSNYS 531_ GDKCS 536_ GPNGQ 541_ ANGDT 546_ VNATL 551_ MQPGV 556_ NGPMG 561_ TNFQV 566_ NTNKG 571_ GGVWE 576_ SGAAN 581_ SQSTS 586_ WGSGN 591_ GANSG 596_ GSRRG 601_ WGTPA 606_ QNTGT 611_ NLPSV 616_ EWNKL 621_ PSNQH 626_ SNDSA 631_ NGNGK 636_ TFTNG 641_ WKSTE 646_ EEDQG 651_ SATSQ 656_ TNEQS 661_ SVWAK 666_ TGGTV 671_ ESDGS 676_ TESTG 681_ RLEEK 686_ GTGES 691_ QSRDR 696_ RKIDQ 701_ HTLLQ 706_ SIVNR 711_ TDLDP 716_ RVLSN 721_ SGWGQ 726_ TPIKQ 731_ NTAWD 736_ TETSP 741_ RGERK 746_ TDNGT 751_ EAWGS 756_ SATQT 761_ FNSGA 766_ CIDKT 771_ SPNGN 776_ DTSSV 781_ SGWGD 786_ PKPAL 791_ RWGDS 796_ KGSNC 801_ QGGWE 806_ DDSAA 811_ TGMVK 816_ SNQWG 821_ NCKEE 826_ KAAWN 831_ DSQKN 836_ KQGWG 841_ DGQKS 846_ SQGWS 851_ VSASD 856_ NWGET 861_ SRNNH 866_ WGEAN 871_ KKSSS 876_ GGSDS 881_ DRSVS 886_ GWNEL 891_ GKTSS 896_ FTWGN 901_ NINPN 906_ NSSGW 911_ DESSK 916_ PTPSQ 921_ GWGDP 926_ PKSNQ 931_ SLGWG 936_ DSSKP 941_ VSSPD 946_ WNKQQ 951_ DIVGS 956_ WGIPP 961_ ATGKP 966_ PGTGW 971_ LGGPI 976_ PAPAK 981_ EEEPT 986_ GWEEP 991_ SPESI 996_ RRKME 1001_ IDDGT 1006_ SAWGD 1011_ PSKYN 1016_ YKNVN 1021_ MWNKN 1026_ VPNGN 1031_ SRSDQ 1036_ QAQVH 1041_ QLLTP 1046_ ASAIS 1051_ NKEAS 1056_ SGSGW 1061_ GEPWG 1066_ EPSTP 1071_ ATTVD 1076_ NGTSA 1081_ WGKPI 1086_ DSGPS 1091_ WGEPI 1096_ AAASS 1101_ TSTWG 1106_ SSSVG 1111_ PQALS 1116_ KSGPK 1121_ SMQDG 1126_ WCGDD 1131_ MPLPG 1136_ NRPTG 1141_ WEEEE 1146_ DVEIG 1151_ MWNSN 1156_ SSQEL 1161_ NSSLN 1166_ WPPYT 1171_ KKMSS 1176_ KGLSG 1181_ KKRRR 1186_ ERGMM 1191_ KGGNK 1196_ QEEAW 1201_ INPFV 1206_ KQFSN 1211_ ISFSR 1216_ DSPEE 1221_ NVQSN 1226_ KMDLS 1231_ GGMLQ 1236_ DKRME 1241_ IDKHS 1246_ LNIGD 1251_ YNRTV 1256_ GKGPG 1261_ SRPQI 1266_ SKESS 1271_ MERNP 1276_ YFDKD 1281_ GIVAD 1286_ ESQNM 1291_ QFMSS 1296_ QSMKL 1301_ PPSNS 1306_ ALPNQ 1311_ ALGSI 1316_ AGLGM 1321_ QNLNS 1326_ VRQNG 1331_ NPSMF 1336_ GVGNT 1341_ AAQPR 1346_ GMQQP 1351_ PAQPL 1356_ SSSQP 1361_ NLRAQ 1366_ VPPPL 1371_ LSPQV 1376_ PVSLL 1381_ KYAPN 1386_ NGGLN 1391_ PLFGP 1396_ QQVAM 1401_ LNQLS 1406_ QLNQL 1411_ SQISQ 1416_ LQRLL 1421_ AQQQR 1426_ AQSQR 1431_ SVPSG 1436_ NRPQQ 1441_ DQQGR 1446_ PLSVQ 1451_ QQMMQ 1456_ QSRQL 1461_ DPNLL 1466_ VKQQT 1471_ PPSQQ 1476_ QPLHQ 1481_ PAMKS 1486_ FLDNV 1491_ MPHTT 1496_ PELQK 1501_ GPSPI 1506_ NAFSN 1511_ FPIGL 1516_ NSNLN 1521_ VNMDM 1526_ NSIKE 1531_ PQSRL 1536_ RKWTT 1541_ VDSIS 1546_ VNTSL 1551_ DQNSS 1556_ KHGAI 1561_ SSGFR 1566_ LEESP 1571_ FVPYD 1576_ FMNSS 1581_ TSPAS 1586_ PPGSI 1591_ GDGWP 1596_ RAKSP 1601_ NGSSS 1606_ VNWPP 1611_ EFRPG 1616_ EPWKG 1621_ YPNID 1626_ PETDP 1631_ YVTPG 1636_ SVINN 1641_ LSINT 1646_ VREVD 1651_ HLRDR 1656_ NSGSS 1661_ SSLNT 1666_ TLPST 1671_ SAWSS 1676_ IRASN 1681_ YNVPL 1686_ SSTAQ 1691_ STSAR 1696_ NSDSK 1701_ LTWSP 1706_ GSVTN 1711_ TSLAH 1716_ ELWKV 1721_ PLPPK 1726_ NITAP 1731_ SRPPP 1736_ GLTGQ 1741_ KPPLS 1746_ TWDNS 1751_ PLRIG 1756_ GGWGN 1761_ SDARY 1766_ TPGSS 1771_ WGESS 1776_ SGRIT 1781_ NWLVL 1786_ KNLTP 1791_ QIDGS 1796_ TLRTL 1801_ CMQHG 1806_ PLITF 1811_ HLNLP 1816_ HGNAL 1821_ VRYSS 1826_ KEEVV 1831_ KAQKS 1836_ LHMCV 1841_ LGNTT 1846_ ILAEF 1851_ ASEEE 1856_ ISRFF 1861_ AQSQS 1866_ LTPSP 1871_ GWQSL 1876_ GSSQS 1881_ RLGSL 1886_ DCSHS 1891_ FSSRT 1896_ DLNHW 1901_ NGAGL 1906_ SGTNC 1911_ GDLHG 1916_ TSLWG 1921_ TPHYS 1926_ TSLWG 1931_ PPSSS 1936_ DPRGI 1941_ SSPSP 1946_ INAFL 1951_ SVDHL 1956_GGGGE
1: Plays a role in RNA-mediated gene silencing by both micro-RNAs (miRNAs) and short interfering RNAs (siRNAs). Required for miRNA-dependent repression of translation and for siRNA-dependent endonucleolytic cleavage of complementary mRNAs by argonaute family proteins. As a scaffolding protein, associates with argonaute proteins bound to partially complementary mRNAs, and can simultaneously recruit CCR4-NOT and PAN deadenylase complexes