Phospholipid phosphatase 5 (EC 3.1.3.4) (EC 3.1.3.81) (Phosphatidic acid phosphatase type 2 domain-containing protein 1B)
1_MGKAA 6_ AAVAF 11_ GAEVG 16_ VRLAL 21_ FAAFL 26_ VTELL 31_ PPFQR 36_ LIQPE 41_ EMWLY 46_ RNPYV 51_ EAEYF 56_ PTKPM 61_ FVIAF 66_ LSPLS 71_ LIFLA 76_ KFLKK 81_ ADTRD 86_ SRQAC 91_ LAASL 96_ ALALN 101_ GVFTN 106_ TIKLI 111_ VGRPR 116_ PDFFY 121_ RCFPD 126_ GLAHS 131_ DLMCT 136_ GDKDV 141_ VNEGR 146_ KSFPS 151_ GHSSF 156_ AFAGL 161_ AFASF 166_ YLAGK 171_ LHCFT 176_ PQGRG 181_ KSWRF 186_ CAFLS 191_ PLLFA 196_ AVIAL 201_ SRTCD 206_ YKHHW 211_ QDVLV 216_ GSMIG 221_ MTFAY 226_ VCYRQ 231_ YYPPL 236_ TDAEC 241_ HKPFQ 246_ DKLVL 251_ STAQK 256_PGDSY
1: Magnesium-independent phospholipid phosphatase with broad substrate specificity (PubMed:17590538). Preferentially catalyzes the conversion of diacylglycerol pyrophosphate into phosphatidate but can also act on phosphatidate and lysophosphatidate (PubMed:17590538). Phospholipid phosphatases are involved in both the synthesis of lipids and the generation or degradation of lipid-signaling molecules (PubMed:17590538)