SHC SH2 domain-binding protein 1
1_MADGS 6_ LTGGG 11_ LEAAA 16_ MAPER 21_ MGWAV 26_ EQELA 31_ SLEKG 36_ LFQDE 41_ DSCSD 46_ CSYRD 51_ KPGSS 56_ LQSFM 61_ PEGKT 66_ FFPEI 71_ FQTNQ 76_ LLFYE 81_ RFRAY 86_ QDYIL 91_ ADCKA 96_ SEVQE 101_ FTAEF 106_ LEKVL 111_ EPSGW 116_ RAVWH 121_ TNVFK 126_ VLVEI 131_ TDVDF 136_ AALKA 141_ VVRLA 146_ EPYLC 151_ DSQVS 156_ TFTME 161_ CMKEL 166_ LDLKE 171_ HRLPL 176_ QELWV 181_ VFDDS 186_ GVFDQ 191_ TALAI 196_ EHVRF 201_ FYQNI 206_ WRSWD 211_ EEEED 216_ EYDYF 221_ VRCVE 226_ PRLRL 231_ HYDIL 236_ EDRVP 241_ SGLIV 246_ DYHNL 251_ LSQCE 256_ ESYRK 261_ FLNLR 266_ SSLSN 271_ CNSDS 276_ EQENI 281_ SMVEG 286_ LKLYS 291_ EMEQL 296_ KQKLK 301_ LIENP 306_ LLRYV 311_ FGYQK 316_ NSNIQ 321_ AKGVR 326_ SSGQK 331_ ITHVV 336_ SSTMM 341_ AGLLR 346_ SLLTD 351_ RLCQE 356_ PGEEE 361_ REIQF 366_ HSDPL 371_ SAINA 376_ CFEGD 381_ TVIVC 386_ PGHYV 391_ VHGTF 396_ SIADS 401_ IELEG 406_ YGLPD 411_ DIVIE 416_ KRGKG 421_ DTFVD 426_ CTGAD 431_ IKISG 436_ IKFVQ 441_ HDAVE 446_ GILIV 451_ HRGKT 456_ TLENC 461_ VLQCE 466_ TTGVT 471_ VRTSA 476_ EFLMK 481_ NSDLY 486_ GAKGA 491_ GIEIY 496_ PGSQC 501_ TLSDN 506_ GIHHC 511_ KEGIL 516_ IKDFL 521_ DEHYD 526_ IPKIS 531_ MVNNI 536_ IHNNE 541_ GYGVV 546_ LVKPT 551_ IFSDL 556_ QENAE 561_ DGTEE 566_ NKALK 571_ IQTSG 576_ EPDVA 581_ ERVDL 586_ EELIE 591_ CATGK 596_ MELCA 601_ RTDPS 606_ EQVEG 611_ NCEIV 616_ NELIA 621_ ASTQK 626_ GQIKK 631_ KRLSE 636_ LGITQ 641_ ADDNL 646_ MSQEM 651_ FVGIV 656_ GNQFK 661_ WNGKG 666_SFGTF
1: May play a role in signaling pathways governing cellular proliferation, cell growth and differentiation. May be a component of a novel signaling pathway downstream of Shc. Acts as a positive regulator of FGF signaling in neural progenitor cells