Casein kinase II subunit alpha 3 (CK II alpha 3) (EC 2.7.11.1) (Casein kinase II alpha 1 polypeptide pseudogene)
1_MSGPV 6_ PSRAR 11_ VYTDV 16_ NTHRP 21_ REYWD 26_ YESHV 31_ VEWGN 36_ QDDYQ 41_ LVRKL 46_ GRGKY 51_ SEVFE 56_ AINIT 61_ NNEKV 66_ VVKIL 71_ KPVKK 76_ KKIKR 81_ EIKIL 86_ ENLRG 91_ GPNII 96_ TLADI 101_ VKDPV 106_ SRTPA 111_ LVFEH 116_ VNNTD 121_ FKQLY 126_ QTLTD 131_ YDIRF 136_ YMYEI 141_ LKALD 146_ YCHSM 151_ GIMHR 156_ DVKPH 161_ NVMID 166_ HEHRK 171_ LRLID 176_ WGLAE 181_ FYHPG 186_ QEYNV 191_ RVASR 196_ YFKGP 201_ ELLVD 206_ YQMYD 211_ YSLDM 216_ WRLGC 221_ MLASM 226_ IFRKE 231_ PFFHG 236_ RDNYD 241_ QLVRI 246_ AKFLG 251_ TEDLY 256_ GYIDK 261_ YNIEL 266_ DPRFN 271_ DILGR 276_ HSRKR 281_ WERFV 286_ HSENQ 291_ HLVSP 296_ EALDF 301_ LDKLL 306_ RYDHQ 311_ SRLTA 316_ REAME 321_ HPYFY 326_ TVVKD 331_ QARMG 336_ SSSMP 341_ GGSTP 346_ VSSAN 351_ VMSGI 356_ SSVPT 361_ PSPLG 366_ PLAGS 371_ PVIAA 376_ ANPLG 381_ MPVPA 386_ATGAQ
1: Probable catalytic subunit of a constitutively active serine/threonine-protein kinase complex that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine. Amplification-dependent oncogene; promotes cell proliferation and tumorigenesis by down-regulating expression of the tumor suppressor protein, PML. May play a role in the pathogenesis of the lung cancer development and progression