Myosin-IIIa (EC 2.7.11.1)
1_MFPLI 6_ GKTII 11_ FDNFP 16_ DPSDT 21_ WEITE 26_ TIGKG 31_ TYGKV 36_ FKVLN 41_ KKNGQ 46_ KAAVK 51_ ILDPI 56_ HDIDE 61_ EIEAE 66_ YNILK 71_ ALSDH 76_ PNVVR 81_ FYGIY 86_ FKKDK 91_ VNGDK 96_ LWLVL 101_ ELCSG 106_ GSVTD 111_ LVKGF 116_ LKRGE 121_ RMSEP 126_ LIAYI 131_ LHEAL 136_ MGLQH 141_ LHNNK 146_ TIHRD 151_ VKGNN 156_ ILLTT 161_ EGGVK 166_ LVDFG 171_ VSAQL 176_ TSTRH 181_ RRNTS 186_ VGTPF 191_ WMAPE 196_ VIACE 201_ QQLDT 206_ TYDAR 211_ CDTWS 216_ LGITA 221_ IELGD 226_ GDPPL 231_ ADLHP 236_ MRALF 241_ KIPRN 246_ PPPKL 251_ RQPEL 256_ WSAEF 261_ NDFIS 266_ KCLTK 271_ DYEKR 276_ PTVSE 281_ LLQHK 286_ FITQI 291_ EGKDV 296_ MLQKQ 301_ LTEFI 306_ GIHQC 311_ MGGTE 316_ KARRE 321_ RIHTK 326_ KGNFN 331_ RPLIS 336_ NLKDV 341_ DDLAT 346_ LEILD 351_ ENTVS 356_ EQLEK 361_ CYSRD 366_ QIYVY 371_ VGDIL 376_ IALNP 381_ FQSLG 386_ LYSTK 391_ HSKLY 396_ IGSKR 401_ TASPP 406_ HIFAM 411_ ADLGY 416_ QSMIT 421_ YNSDQ 426_ CIVIS 431_ GESGA 436_ GKTEN 441_ AHLLV 446_ QQLTV 451_ LGKAN 456_ NRTLQ 461_ EKILQ 466_ VNNLV 471_ EAFGN 476_ ACTII 481_ NDNSS 486_ RFGKY 491_ LEMKF 496_ TSSGA 501_ VVGAQ 506_ ISEYL 511_ LEKSR 516_ VIHQA 521_ IGEKN 526_ FHIFY 531_ YIYAG 536_ LAEKK 541_ KLAHY 546_ KLPEN 551_ KPPRY 556_ LQNDH 561_ LRTVQ 566_ DIMNN 571_ SFYKS 576_ QYELI 581_ EQCFK 586_ VIGFT 591_ MEQLG 596_ SIYSI 601_ LAAIL 606_ NVGNI 611_ EFSSV 616_ ATEHQ 621_ IDKSH 626_ ISNHT 631_ ALENC 636_ ASLLC 641_ IRADE 646_ LQEAL 651_ TSHCV 656_ VTRGE 661_ TIIRP 666_ NTVEK 671_ ATDVR 676_ DAMAK 681_ TLYGR 686_ LFSWI 691_ VNCIN 696_ SLLKH 701_ DSSPS 706_ GNGDE 711_ LSIGI 716_ LDIFG 721_ FENFK 726_ KNSFE 731_ QLCIN 736_ IANEQ 741_ IQYYY 746_ NQHVF 751_ AWEQN 756_ EYLNE 761_ DVDAR 766_ VIEYE 771_ DNWPL 776_ LDMFL 781_ QKPMG 786_ LLSLL 791_ DEESR 796_ FPKAT 801_ DQTLV 806_ EKFEG 811_ NLKSQ 816_ YFWRP 821_ KRMEL 826_ SFGIH 831_ HYAGK 836_ VLYNA 841_ SGFLA 846_ KNRDT 851_ LPTDI 856_ VLLLR 861_ SSDNS 866_ VIRQL 871_ VNHPL 876_ TKTGN 881_ LPHSK 886_ TKNVI 891_ NYQMR 896_ TSEKL 901_ INLAK 906_ GDTGE 911_ ATRHA 916_ RETTN 921_ MKTQT 926_ VASYF 931_ RYSLM 936_ DLLSK 941_ MVVGQ 946_ PHFVR 951_ CIKPN 956_ SERQA 961_ RKYDK 966_ EKVLL 971_ QLRYT 976_ GILET 981_ ARIRR 986_ LGFSH 991_ RILFA 996_ NFIKR 1001_ YYLLC 1006_ YKSSE 1011_ EPRMS 1016_ PDTCA 1021_ TILEK 1026_ AGLDN 1031_ WALGK 1036_ TKVFL 1041_ KYYHV 1046_ EQLNL 1051_ MRKEA 1056_ IDKLI 1061_ LIQAC 1066_ VRAFL 1071_ CSRRY 1076_ QKIQE 1081_ KRKES 1086_ AIIIQ 1091_ SAARG 1096_ HLVRK 1101_ QRKEI 1106_ VDMKN 1111_ TAVTT 1116_ IQTSD 1121_ QEFDY 1126_ KKNFE 1131_ NTRES 1136_ FVKKQ 1141_ AENAI 1146_ SANER 1151_ FISAP 1156_ NNKGS 1161_ VSVVK 1166_ TSTFK 1171_ PEEET 1176_ TNAVE 1181_ SNNRV 1186_ YQTPK 1191_ KMNNV 1196_ YEEEV 1201_ KQEFY 1206_ LVGPE 1211_ VSPKQ 1216_ KSVKD 1221_ LEENS 1226_ NLRKV 1231_ EKEEA 1236_ MIQSY 1241_ YQRYT 1246_ EERNC 1251_ EESKA 1256_ AYLER 1261_ KAISE 1266_ RPSYP 1271_ VPWLA 1276_ ENETS 1281_ FKKTL 1286_ EPTLS 1291_ QRSIY 1296_ QNANS 1301_ MEKEK 1306_ KTSVV 1311_ TQRAP 1316_ ICSQE 1321_ EGRGR 1326_ LRHET 1331_ VKERQ 1336_ VEPVT 1341_ QAQEE 1346_ EDKAA 1351_ VFIQS 1356_ KYRGY 1361_ KRRQQ 1366_ LRKDK 1371_ MSSFK 1376_ HQRIV 1381_ TTPTE 1386_ VARNT 1391_ HNLYS 1396_ YPTKH 1401_ EEINN 1406_ IKKKD 1411_ NKDSK 1416_ ATSER 1421_ EACGL 1426_ AIFSK 1431_ QISKL 1436_ SEEYF 1441_ ILQKK 1446_ LNEMI 1451_ LSQQL 1456_ KSLYL 1461_ GVSHH 1466_ KPINR 1471_ RVSSQ 1476_ QCLSG 1481_ VCKGE 1486_ EPKIL 1491_ RPPRR 1496_ PRKPK 1501_ TLNNP 1506_ EDSTY 1511_ YYLLH 1516_ KSIQE 1521_ EKRRP 1526_ RKDSQ 1531_ GKLLD 1536_ LEDFY 1541_ YKEFL 1546_ PSRSG 1551_ PKEHS 1556_ PSLRE 1561_ RRPQQ 1566_ ELQNQ 1571_ CIKAN 1576_ ERCWA 1581_ AESPE 1586_ KEEER 1591_ EPAAN 1596_ PYDFR 1601_ RLLRK 1606_ TSQRR 1611_RLVQQ
1: Actin-dependent motor protein with a protein kinase activity, playing an essential role in hearing (PubMed:12032315, PubMed:29880844, PubMed:34788109). Probably also plays a role in vision. Required for normal cochlear hair bundle development and hearing. Plays an important role in the early steps of cochlear hair bundle morphogenesis. Influences the number and lengths of stereocilia to be produced and limits the growth of microvilli within the forming auditory hair bundles thereby contributing to the architecture of the hair bundle, including its staircase pattern. Involved in the elongation of actin in stereocilia tips by transporting the actin regulatory factor ESPN to the plus ends of actin filaments (PubMed:29880844, PubMed:34788109)